Ibuprofen - instructions for use, dose, side effects, contraindications

Pharmacodynamics:Has analgesic, anti-inflammatory and antipyretic effect. The mechanism of action of ibuprofen is due to inhibition of the biosynthesis of prostaglandins - mediators of pain and inflammation.

The drug lasts up to 8 hours.

Indications:

Ibuprofen rectal suppositories (for children) are used from 3 months of life to 2 years as an antipyretic agent for acute respiratory infections, influenza, childhood infections, post-vaccination reactions and other infectious and inflammatory diseases accompanied by fever.

The drug is used as an anesthetic for pain syndrome of mild or moderate intensity, including: headache and toothache, neuralgia, pain in the ears and throat, pain in case of ligament injuries and other types of pain.

Contraindications:

Ibuprofen should not be used when:

- hypersensitivity to ibuprofen, acetylsalicylic acid or other non-steroidal anti-inflammatory drugs (NSAIDs), as well as to other components of the drug;

- bronchial asthma, hives, rhinitis, triggered by the use of acetylsalicylic acid (salicylates) or other NSAIDs;

- if the child has ulcerative lesions of the gastrointestinal tract (GIT);

- active gastrointestinal hemorrhage;

- inflammatory bowel disease;

- with confirmed hypokalemia;

- blood diseases: hypocoagulation, leukopenia, hemophilia;

- renal and / or liver failure;

- hearing loss.

Carefully:

You should consult your doctor before you apply ibuprofen, if the child:

- takes other painkillers;

- has a history of: peptic ulcer, gastritis, ulcerative colitis, gastrointestinal bleeding;

- suffers from liver or kidney disease;

- takes indirect anticoagulants (oral medications that reduce blood clotting), drugs for lowering blood pressure, glucocorticosteroids, antiaggregants, diuretics (drugs for increasing urine output), lithium preparations, methotrexate;

- suffers from bronchial asthma, hives.

Dosing and Administration:

Ibuprofen - suppositories, specially developed for children. The drug is used rectally.Read the instructions carefully before taking the drug.

Fever (fever) and pain: dosage for children depends on the age and body weight of the child. A single dose is 5-10 mg / kg of the child's body weight 3-4 times a day. The maximum daily dose should not exceed 30 mg per kg of body weight of the child per day.

Children aged 3-9 months (5.5 kg - 8.0 kg): 1 suppository (60 mg) 3 times within 24 hours after 6-8 hours, not more than 180 mg in the sutri.

Children aged 9 months - 2 years (8.0 kg - 12.5 kg): 1 suppository (60 mg) 4 times within 24 hours after 6 hours, no more than 240 mg per day.

Postimmunization fever: one suppository for children under the age of 1 year, after 1 year, if necessary, another suppository in 6 hours. Duration of treatment:

- not more than 3 days as an antipyretic agent;

- not more than 5 days as an anesthetic.

If the fever persists, talk to your doctor. Do not exceed the indicated dose.

Side effects:

When using the drug, side effects are rare, but the following side effects may occur:

From the digestive tract: nausea, vomiting, a feeling of discomfort, or epigastric pain, laxative effect, possibly erosive ulcerative lesions, bleeding.

Allergic reactions: skin rash, itching, urticaria, exacerbation of bronchial asthma, angioedema, anaphylactoid reactions, anaphylactic shock, bronchospasm, fever, erythema multiforme exudative (including Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome).

From the nervous system: headache, dizziness, psychomotor agitation, insomnia.

The cardiovascular system: tachycardia, increased blood pressure.

From the hematopoiesis: anemia, thrombocytopenia, agranulocytosis, leukopenia.

From the urinary system: impaired renal function, cystitis.

If these or other side effects occur, discontinue use and consult a doctor.

Overdose:

Problems with overdose occur very rarely, but if you accidentally exceed the recommended dose, consult a doctor immediately.

Symptoms: abdominal pain, nausea, vomiting, headache, rapid eye movements (nystagmus), shortness of breath, cyanotic lips and nose, bradycardia, tachycardia.

Interaction:

Simultaneous use of Ibuprofen with anticoagulants may lead to an increase in their effect.

Ibuprofen increases the concentration of digoxin, phenytoin, methotrexate, lithium in blood plasma when used simultaneously with these drugs.

The use of ibuprofen along with diuretics and antihypertensive agents reduces their effectiveness.

Increases the side effects of mineralocorticosteroids and glucocorticosteroids.

Form release / dosage:

Suppositories rectal (for children) 60 mg.

Packaging:There are 5 suppositories in a contiguous cell package.

2 contour mesh packs together with instructions for use are placed in a pack of cardboard.

Storage conditions:In a dry, protected from light place at a temperature of no higher than 25 ° C. Keep out of the reach of children.

Shelf life:2 years. Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-000778

Date of registration:29.09.2011

The owner of the registration certificate:RAFARMA, CJSC RAFARMA, CJSC Russia

Manufacturer: & nbsp

RAFARMA, JSC Russia

Information update date: & nbsp27.05.2014

Illustrated instructions

Instructions

Ibuprofen (Ibuprofen)