Active substanceEthanolEthanol
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  • Dosage form: & nbspsolution for external use and preparation of dosage forms
    Composition:

    90%

    70%

    Active substances:

    Ethanol (ethyl alcohol) 95 %

    927 grams

    675 grams

    Excipients:

    Purified water

    73g

    325 g

    Description:Transparent, colorless mobile liquid with a characteristic smell of alcohol.
    Pharmacotherapeutic group:antiseptic
    ATX: & nbsp

    D.08.A.X.08   Ethanol

    Pharmacodynamics:

    Antimicrobial, with local application has an antiseptic effect (denaturing proteins of microorganisms). It is active against gram-positive and gram-negative bacteria and viruses. Antiseptic activity increases with increasing ethanol concentration. For disinfecting the skin, 70% solution is used, penetrating deeper layers of the epidermis better than 90%, which has a tanning effect on the skin and mucous membranes.

    It is a solvent for a number of drugs (LS), as well as an extractant for a number of substances contained in medicinal plant raw materials.

    Pharmacokinetics:When used externally, it is absorbed from the surface of the skin and mucous membranes into the systemic circulation. In the metabolism of the drug involved isoenzyme CYP2E1, inductor of which it is.
    Indications:

    Treatment of the initial stages of diseases: furuncle, panaritium, mastitis; the treatment of the hands of the surgeon, (the methods of Fürbringer, Alfred), the operation field (including those with hypersensitivity to other antiseptics, in children and operations on areas with thin skin in adults - neck, face).

    Preservation of biological material, production of medicinal forms for external use, tinctures, extracts.
    Contraindications:

    Hypersensitivity.

    Carefully:

    Pregnancy, lactation, children's age.

    Pregnancy and lactation:

    Breastfeeding mothers and pregnant women apply ethyl alcohol externally with caution because of the possible resorptive effect on the body.

    Dosing and Administration:

    Outer in the form of lotions.To process the surgical field and pre-surgical disinfection of the hands of the surgeon, 70% solution is used, for compresses and rubbing (to avoid burns) it is recommended to use 40% solution.

    90% solution must be diluted to the required concentrations and used, according to indications.

    Drugs made on the basis of ethanol are used in accordance with the instructions for the medical use of these dosage forms.

    Side effects:

    Allergic reactions, skin burns, hyperemia and tenderness of the skin at the site of application compress.

    When used externally, it is partially absorbed into the skin and mucous membranes and may have a resorptive general toxic effect (central nervous system depression).

    Overdose:

    When external application of an overdose was not noted.

    Interaction: Not installed.
    Special instructions:

    Ethanol for external use is partially absorbed through the skin and mucous membranes, which should be taken into account when used in children, pregnant women and lactation.

    Effect on the ability to drive transp. cf. and fur:When driving and other mechanisms, use the drug with caution because of the possible resorptive effect on the body.
    Form release / dosage:Solution for external use and preparation of medicinal forms, 90% and 70%.
    Packaging:

    To 50, 100 ml in bottles of glass, sealed with stoppers, polyethylene and screwed caps, or in glass bottles ukuporennyh caps aluminum.

    Each vial with the instruction for use is placed in a pack.

    By 10 or 21.5 liters in polyethylene cans (for hospitals, production departments of pharmacies, bureau of pathological anatomical and forensic medical examination).

    For hospitals - with application instructions for use.

    Storage conditions:

    At a temperature of 12 to 15 ° C in a well-ukuporennoy container, away from fire.

    Keep out of the reach of children's day.

    Shelf life:

    2 years.

    Do not use after expiry date.

    Terms of leave from pharmacies:On prescription
    Registration number:LP-001167
    Date of registration:11.11.2011
    Date of cancellation:2016-11-11
    The owner of the registration certificate:SPbNIIVS FMBA, FSUE SPbNIIVS FMBA, FSUE Russia
    Manufacturer: & nbsp
    Representation: & nbspSPbNIIVS FMBA, FSUESPbNIIVS FMBA, FSUERussia
    Information update date: & nbsp06.10.2015
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