Active substanceEthanolEthanol
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  • Dosage form: & nbspsolution for external use and preparation of dosage forms
    Composition:

    Composition per 100 g

    70%

    Active substance:

    Ethanol (ethyl alcohol) 95%

    67.5 g

    Excipient:

    Purified water

    32.5 g

    Description:

    Transparent colorless mobile liquid with a characteristic smell of alcohol.

    Pharmacotherapeutic group:antiseptic
    ATX: & nbsp

    D.08.A.X.08   Ethanol

    Pharmacodynamics:

    Antimicrobial, with local application has an antiseptic effect (denaturing proteins of microorganisms). It is active against gram-positive and gram-negative bacteria and viruses. Antiseptic activity increases with increasing ethanol concentration.

    For disinfecting the skin, 70% solution is used, penetrating deeper layers of the epidermis better than 90%, which has a tanning effect on the skin and mucous membranes.

    It is a solvent for a number of drugs, as well as an extractant for a number of substances contained in medicinal plant raw materials.

    Pharmacokinetics:

    When used externally, it is absorbed from the surface of the skin and mucous membranes into the systemic circulation. In the metabolism of the drug involved isoenzyme CYP2E1, the inductor of which it is.

    Indications:

    Treatment of the initial stages of diseases: furuncle, panaritium, mastitis; treatment of the hands of the surgeon (the methods of Fürbringer, Alfred), the operation field (including those with sensitivity to other antiseptics, in children and operations on areas with thin skin in adults - neck, face).

    Preservation of biological material, production of medicinal forms for external use, tinctures, extracts.

    Contraindications:

    Hypersensitivity.

    Carefully:

    Pregnancy, lactation, children's age.

    Dosing and Administration:

    Outer, in the form of lotions, compresses and rubs. To process the surgical field and pre-surgical disinfection of the hands of the surgeon, 70% solution is used, it is recommended to use a 40% solution for compresses and wipes (to avoid burns).

    70% solution must be diluted to the required concentration and used according to the indications.

    The drugs prepared on the basis of ethanol are used in accordance with the instructions for the medical use of these dosage forms.

    Side effects:

    Allergic reactions, skin burns, hyperemia and soreness of the skin at the site of compression.

    When used externally, it is partially absorbed through the skin and mucous membranes and may have a resorptive general toxicity (central nervous system depression).

    Special instructions:

    In external application, ethanol is partially absorbed through the skin and mucous membranes, which must be taken into account when used in children, pregnant women and lactation.

    Form release / dosage:

    Solution for external use and preparation of dosage forms, 70%.

    Packaging:

    To 50, 100 ml in bottles or jars of colorless or orange glass, sealed with stoppers, polyethylene and screwed caps or aluminum caps rolled up with gaskets.

    To 50, 100 ml into bottles polymeric corked polymeric plugs or stoppers with sealing elements and polymeric covers.

    Each bottle or jar with instructions for use is placed in a pack of cardboard.

    For 50 or 60 bottles with an equal number of instructions for use are placed in a cardboard box (for hospitals).

    By 5, 10, 15, 20, 21.5, 25 or 30 liters in polyethylene cans (for production departments of pharmacies and hospitals.

    Storage conditions:

    In a well ukuporennoy container.

    Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:LSR-001054/10
    Date of registration:21.11.2012
    The owner of the registration certificate:SAMARAHEDPROM, JSC SAMARAHEDPROM, JSC Russia
    Manufacturer: & nbsp
    Representation: & nbspSAMARAHEDPROM, JSCSAMARAHEDPROM, JSC
    Information update date: & nbsp06.10.2015
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