Active substanceEthanolEthanol
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  • Dosage form: & nbsptooncentrate for the preparation of a solution for external use and preparation of dosage forms
    Composition:Per 100 ml:

    Active substance: ethiol alcohol, substance-liquid 95%.

    Description:

    Transparent, colorless, mobile, volatile liquid with a characteristic alcohol smell.

    Pharmacotherapeutic group:Antiseptic
    ATX: & nbsp

    D.08.A.X.08   Ethanol

    Pharmacodynamics:

    Antimicrobial, with local application has an antiseptic effect (denaturing proteins of microorganisms).

    Active with respect to Gram-positive and gram-negative bacteria and viruses.

    Antiseptic activity increases with increasing ethanol concentration.

    For disinfecting the skin, 70% solution is used, penetrating deeper layers of the epidermis better than 90-95%, which has a tanning effect on the skin and mucous membranes.

    It is a solvent for a number of medicinal products, as well as an extractant for a number of substances contained in medicinal plant raw materials.

    Pharmacokinetics:

    PWhen applied externally, it is absorbed from the surface of the skin and mucous membranes into the systemic circulation.

    In the metabolism of the drug involved isoenzyme CYP2E1, inductor of which it is.

    Indications:

    Treatment of the initial stages of diseases: furuncle, panaritium, mastitis; the treatment of the hands of the surgeon (the methods of Fürbringer, Alfred), the operating field (including those with heightened sensitivity to other antiseptics, in children and operations on areas with thin skin in adults - neck, face).

    Preservation of biological material, production of medicinal forms for external use, tinctures, extracts.

    Contraindications:Hypersensitivity.
    Carefully:

    Pregnancy, lactation, children's age.

    Pregnancy and lactation:

    Use during pregnancy and lactation is permitted if the benefit to the mother exceeds the potential risk to the fetus and the baby.

    Dosing and Administration:

    Outer, in the form of lotions, compresses, wipes.

    For the treatment of the operating field and the preoperative disinfection of the hands of the surgeon, 70% solution, for compresses and wipes (to avoid burns) it is recommended to use a 40% solution.

    95% of the drug should be diluted to the required concentrations.

    Side effects:

    Allergic reactions, skin burns, hyperemia and soreness of the skin at the site of compression.

    When used externally, it is partially absorbed through the skin and mucous membranes and may have a resorptive general toxicity (central nervous system depression).

    Overdose:No data available.
    Interaction:Not studied.
    Special instructions:

    In external application, ethanol is partially absorbed through the skin and mucous membranes, which must be taken into account when used in children, pregnant women and lactation.

    Do not use near open flames.

    Effect on the ability to drive transp. cf. and fur:

    In sensitive patients or with prolonged use is possible. reduction of psychomotor reactions, which should be taken into account when driving vehicles, working with mechanisms, etc.

    For drugs prepared on the basis of ethanol,The impact on the ability to drive a vehicle and potentially other dangerous mechanisms is determined in accordance with the instructions for medical use for these dosage forms.

    Form release / dosage:

    Concentrate for the preparation of solution for external use and preparation of medicinal forms, 95%.

    Packaging:

    To 25, 50, 100 ml in vials of glass-colored liquid colorless or dark glass ukuporennye with polyethylene stoppers and screwed caps or caps aluminum.

    To 25, 50, 100 ml in polymeric bottles made of polyethylene terephthalate, sealed with a screw cap or cap of the first opening control system.

    To 25, 50, 100 ml into polymeric bottles made of polyethylene complete with a cover with a control opening.

    By 25, 50, 100 ml polyethylene bottles made of polyethylene of polypropylene or polyethylene terephthalate, complete with a cover with a control opening.

    Each vial with instructions for use is placed in a pack of cardboard.

    For 40 bottles of 100 ml or 70 bottles of 50 ml or 70 bottles of 25 ml with an equal number of instructions for use are placed in a box or box of cardboard (for hospitals).

    For 40 bottles of 100 ml or 70 bottles of 50 ml or 70 bottles of 25 ml with an equal number of instructions for use are placed in a box of cardboard or a box of cardboard (for production departments of pharmacies).

    By 1, 3, 5, 10, 21.5, 31.5 liters in polyethylene cans (for production departments of pharmacies).

    By 1, 3, 5, 10, 21.5, 31.5 liters in polyethylene cans (for hospitals).

    For each bottle, canister, box, box label.

    On the canister (for hospitals) paste the instructions for use.
    Storage conditions:

    At a temperature of no higher than 25 ° C, in a well-ukuporennoy container, far from the fire.

    In a place inaccessible to children.

    Shelf life:

    5 years.

    Do not use after the expiration date indicated on the package.
    Terms of leave from pharmacies:On prescription
    Registration number:LP-003490
    Date of registration:09.03.2016
    Expiration Date:09.03.2021
    The owner of the registration certificate:MEDHIMPROM ПХФК, ОАО MEDHIMPROM ПХФК, ОАО Russia
    Manufacturer: & nbsp
    Information update date: & nbsp14.04.2018
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