Active substanceEthanolEthanol
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  • Dosage form: & nbspsolution for external use and preparation of dosage forms
    Composition:

    Ingredients per 100 g:

    40%

    70%

    90%

    Active substance:

    Ethanol (ethyl alcohol) 95%

    36.0 g

    67.5 g

    92.7 g

    Excipient:

    Purified water

    64.0 g

    32.5 g

    7.3 g

    Description:Transparent, colorless, mobile liquid with a characteristic smell of alcohol.
    Pharmacotherapeutic group:antiseptic
    ATX: & nbsp

    D.08.A.X.08   Ethanol

    Pharmacodynamics:

    Antimicrobial, with local application has an antiseptic effect (denaturing proteins of microorganisms). It is active against gram-positive and gram-negative bacteria and viruses. Antiseptic activity increases with increasing ethanol concentration.

    To disinfect the skin use 70% a solution penetrating deeper layers of the epidermis is better than 90-95%, which has a tanning effect on the skin and mucous membranes.

    With systemic application it has the ability to cause analgesia and general anesthesia. The cells of the central nervous system are most sensitive to ethanol, especially the cells of the cerebral cortex, affecting, ethanol causes a characteristic alcoholic excitement associated with the weakening of the processes of inhibition. Then comes the weakening of the processes of excitation in the cortex, the inhibition of the spinal cord and the medulla oblongata with suppression of the activity of the respiratory center.

    It is a solvent for a number of drugs, as well as an extractant for a number of substances contained in medicinal plant raw materials.

    Pharmacokinetics:

    If, the external application is absorbed from, the surface of the skin and mucous membranes in systemic blood flow. In the metabolism, the drug is involved in the isozyme CYP2E1, inductor of which it is.

    Indications:

    Treatment of the initial stages of diseases: furuncle, panaritium, mastitis; treatment of the hands of the surgeon (the methods of Fürbringer, Alfred), the operation field (including those with sensitivity to other antiseptics, in children and operations on areas with thin skin in adults - neck, face).

    Preservation, biological material, the manufacture of dosage forms for external application, tinctures, extracts.

    Contraindications:

    Hypersensitivity.

    Carefully:

    Pregnancy, lactation, children's age.

    Pregnancy and lactation:

    Use during pregnancy and lactation is permitted if the benefit to the mother exceeds the potential risk to the fetus and the baby.

    Dosing and Administration:

    Outer, in the form of lotions.

    For the treatment, surgical field and pre-surgical disinfection of the hands of the surgeon use: 70% solution, for compresses and rubbing, (to avoid burns) it is recommended to use 40% solution.

    90% solution should be diluted to the required concentrations and used according to indications.

    Drugs prepared on the basis of ethanol are used in accordance with the instructions for the medical use of these dosage forms.

    Side effects:

    Allergic reactions; Skin burns, flushing and soreness of the skin in the place of compressing.

    When used externally, it is partially absorbed through the skin, and the mucous membranes and can have a resorptive general toxic effect (central nervous system depression).

    Overdose:

    No data available.

    Interaction:

    No data available.

    Special instructions:

    In external application, ethanol is partially absorbed through the skin and mucous membranes, which must be taken into account when used in children, pregnant women and lactation.

    Effect on the ability to drive transp. cf. and fur:

    A medicinal preparation used as a solution for external use does not affect the ability to drive a car and other potentially dangerous mechanisms. For drugs based on ethanol, the influence on the ability to drive a vehicle and potentially other dangerous mechanisms is determined in accordance with the instructions for medical use for these dosage forms.

    Form release / dosage:

    Solution for external use and preparation of dosage forms, 40%, 70% and 90%.

    Packaging:

    To 25, 50, 100 ml in bottles of glass with a screw neck of orange glass or in glass bottles with a screw neck of orange or colorless glass,Sealed with aluminum rolled up caps with a gasket or sealed with polyethylene plugs and screw caps.

    For 25, 50, 100 ml in polymer bottles made of polyethylene terephthalate for medicines.

    The vials are sealed with a screw cap of the "push and turn" system with the first opening control or the cap of the first autopsy control system.

    For 25, 50, 100 ml in bottles of polyethylene for medicines from high-density polyethylene of low density, complete with a cover with a control opening.

    Each bottle, together with the instructions for use, is placed in a pack of cardboard.

    For 40 bottles of 100 ml or 70 bottles of 50 ml or 70 bottles of 25 ml bottles with an equal number of instructions for use will be placed in a box of cardboard (for hospitals).

    For 40 bottles of 100 ml or 70 bottles of 50 ml or 70 bottles of 25 ml of bottles with an equal number of instructions for use are placed in a box of cardboard (for production departments of pharmacies).

    On the box (for hospitals), (for production departments of pharmacies) glue a label from paper label or writing or self-adhesive labels.

    By 1, 3, 5, 10, 21.5, 31.5 liters in polyethylene cans of low-density polyethylene (for hospitals).

    By 1, 3, 5, 10, 21,5, 31,5 l in polyethylene jerricans from low pressure polyethylene (for production departments of drugstores).

    On the canister (for hospitals), (for production departments of pharmacies) glue a label from paper label or writing or self-adhesive labels.

    On the canister (for hospitals), (for production departments of pharmacies) glue the instructions for use from paper label or writing or self-adhesive.

    Storage conditions:

    In a well ukuporennoy packaging, away from sources of fire, at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    5 years.

    Do not use after the expiration date indicated on the package.
    Terms of leave from pharmacies:On prescription
    Registration number:LS-002101
    Date of registration:09.08.2011
    The owner of the registration certificate:MEDHIMPROM ПХФК, ОАО MEDHIMPROM ПХФК, ОАО Russia
    Manufacturer: & nbsp
    Information update date: & nbsp10.10.2015
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