Active substanceEthanolEthanol
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  • Dosage form: & nbspsolution for external use and preparation of dosage forms
    Composition:

    Ethyl alcohol (ethanol) rectified 95%, purified water.

    Description:Transparent, colorless, mobile liquid with a characteristic alcohol smell.
    Pharmacotherapeutic group:antiseptic
    ATX: & nbsp

    D.08.A.X.08   Ethanol

    Pharmacodynamics:

    Antimicrobial, with local application has an antiseptic effect (denaturing proteins of microorganisms). It is active against gram-positive and gram-negative bacteria and viruses. Antiseptic activity increases with increasing ethanol concentration.

    To disinfect the skin, 70% solution is used, penetrating deeper layers of the epidermis better than 95%, which has a tanning effect on the skin and mucous membranes.

    It is a solvent for a number of medicinal products, as well as an extractant for a number of substances contained in medicinal plant raw materials.

    Pharmacokinetics:

    When used externally, it is absorbed from the surface of the skin and mucous membranes into the systemic circulation. In the metabolism of the drug involved isoenzyme CYP2E1, the inductor of which it is.

    Indications:

    Treatment of the initial stages of diseases: furuncle, panaritium, mastitis; treatment of the hands of the surgeon (the methods of Fürbringer, Alfred), the operating field (including those with sensitivity to other antiseptics, in children and operations on areas with thin skin in adults - neck, face).

    Preservation of biological material, production of medicinal forms for external use, tinctures, extracts.

    Contraindications:

    Hypersensitivity.

    Carefully:

    Pregnancy, lactation, children's age.

    Pregnancy and lactation:

    Special studies of use during pregnancy and lactation were not conducted.

    The decision to use should be taken, assessing the ratio of possible risks to the child and benefits for the mother.

    Dosing and Administration:

    Outer, in the form of lotions.For the treatment of the operating field and the preoperative disinfection of the hands of the surgeon, 70% solution, for compresses and wipes (to avoid burns) it is recommended to use a 40% solution.

    95% solution must be diluted to the required concentrations and used according to indications.

    Drugs made on the basis of ethanol are used in accordance with the instructions for the medical use of these dosage forms.

    Side effects:

    Allergic reactions, skin burns, hyperemia and soreness of the skin at the site of compression.

    When used externally, it is partially absorbed through the skin and mucous membranes and may have a resorptive general toxicity (central nervous system depression).

    Special instructions:

    Ethanol for external use is partially absorbed through the skin and mucous membranes, which should be taken into account when using itenin children, pregnant women and during lactation.

    It is necessary to refrain from carrying out potentially dangerous activities requiring special attention and quick reactions (driving and other vehicles, working with moving mechanisms, dispatcher and operator work, etc.).

    Form release / dosage:

    Solution for external use and preparation of medicinal forms, 95%.

    Packaging:

    By 21.5 liters and 10.0 liters in polyethylene cans (for production departments of pharmacies).

    To 100 ml in bottles of orange glass, ukuporennyh aluminum caps with perforation. Each bottle is placed in a pack of cardboard box. On the package indicate the full text of the instructions for use.

    Storage conditions:

    At a temperature of 12 to 15 ° C, in a well-ukuporennoy container, away from fire.

    Keep out of the reach of children.

    Shelf life:

    5 years.

    Do not use after the expiration date printed on the package.

    Terms of leave from pharmacies:On prescription
    Registration number:P N002413 / 01
    Date of registration:17.06.2008
    The owner of the registration certificate:ARMAVIR DISTRICT PHARMACEUTICAL BASE, OJSC ARMAVIR DISTRICT PHARMACEUTICAL BASE, OJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp09.10.2015
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