Active substanceEthanolEthanol
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  • Dosage form: & nbspsolution for external use and preparation of dosage forms
    Composition:

    Ingredients per 100 g:

    Active substance:

    Ethanol (ethyl alcohol) 95%

    67.5 g

    Excipients:

    Purified water

    32.5 g

    Description:

    Transparent, colorless, mobile liquid with a characteristic smell of alcohol.

    Pharmacotherapeutic group:antiseptic
    ATX: & nbsp

    D.08.A.X.08   Ethanol

    Pharmacodynamics:

    Antimicrobial, with local application has an antiseptic effect (denaturing proteins of microorganisms). It is active against gram-positive and gram-negative bacteria and viruses. Antiseptic activity increases with increasing ethanol concentration.

    To disinfect the skin use 70% A solution penetrating deeper layers of the epidermis is better than 90%, which has a tanning effect on the skin and mucous membranes.

    It is a solvent for a number of medicinal products, as well as an extractant for a number of substances contained in medicinal plant raw materials.

    Pharmacokinetics:

    When used externally, it is absorbed from the surface of the skin and mucous membranes into the systemic circulation. In the metabolism of the drug involved isoenzyme CYP2E1, the inductor of which it is.

    Indications:

    Treatment of the initial stages of diseases: furuncle, panaritium, mastitis; the treatment of the hands of the surgeon (the methods of Fürbringer, Alfred), the operating field (including those with sensitivity to other antiseptics, children and operations on areas with thin skin in adults - neck, face).

    Preservation of biological material, production of medicinal forms for external use, tinctures, extracts.

    Contraindications:

    Hypersensitivity.

    Carefully:

    Pregnancy, lactation, children's age.

    Dosing and Administration:

    Outer, in the form of lotions, compresses and rubs. To process the surgical field and pre-surgical disinfection of the hands of the surgeon, 70% solution is used, it is recommended to use a 40% solution for compresses and wipes (to avoid burns).

    70% solution must be diluted to the required concentration and used according to the indications.

    Drugs made on the basis of ethanol are used in accordance with the instructions for the medical use of these dosage forms.

    Side effects:

    Allergic reactions, skin burns, hyperemia and soreness of the skin at the site of compression.

    When used externally, it is partially absorbed through the skin and mucous membranes and may have a resorptive general toxicity (central nervous system depression).

    Overdose:

    With external application, an overdose is unknown.

    Interaction:

    When using ethyl alcohol is internally compatible with nitrofurans: there is an increase in toxicity of the latter.

    With the joint use of ethyl alcohol and oral antidiabetics, sulfanilic acid derivatives, the possible development of hypoglycemic coma.

    Alcohol reduces the effectiveness of thiamine, increases the risk of stomach ulcers when combined with an acid acetylsalicylic.

    When combined with sedatives of different groups - a significant difficulty in breathing.

    Special instructions:

    In external application, ethanol is partially absorbed through the skin and mucous membranes, which must be taken into account when used in children, pregnant women and lactation.

    The general effect of alcohol can be complicated by stopping breathing and working the heart. In addition, an alcohol having intoxicating action therefore its reception may entail inappropriate utterances and actions, and receiving a large dose can cause loss of consciousness. In this case, the overall effect of alcohol is characterized by a decrease in the intensity of mental and physical performance.

    Effect on the ability to drive transp. cf. and fur:

    During the period of taking the drug, it is not recommended to drive vehicles and engage in other potentially dangerous activities requiring rapidity of psychomotor reactions.

    Form release / dosage:Solution for external use and preparation of dosage forms, 70%.
    Packaging:

    At 50, 100 ml glass vials of amber glass screw neck, sealed with plastic stoppers and screw caps.

    Each bottle with instructions for use is placed in a pack of cardboard box for consumer packaging.

    For 30 or 60 bottles of 50 ml or 15 or 30 bottles of 100 ml with an equal number of instructions for use are placed in a box of cardboard or corrugated cardboard, or in a stack of paper bagging or wrapping (for hospitals).

    Storage conditions:

    In a well-ukuporennoy container, away from the fire.

    Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use after expiry date.

    Terms of leave from pharmacies:On prescription
    Registration number:LP-000497
    Date of registration:01.03.2011
    The owner of the registration certificate:Tyumen Chemical - Pharmaceutical Plant, OJSC Tyumen Chemical - Pharmaceutical Plant, OJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp06.10.2015
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