Active substanceEthanolEthanol
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  • Dosage form: & nbspsolution for external use and preparation of dosage forms
    Composition:A mixture of ethanol and water containing 95% by volume of ethyl alcohol.
    Description:Transparent colorless mobile volatile liquid with a characteristic alcohol smell.
    Pharmacotherapeutic group:antiseptic
    ATX: & nbsp

    D.08.A.X.08   Ethanol

    Pharmacodynamics:

    Antimicrobial, with local application has an antiseptic effect (denaturing proteins of microorganisms). It is active against gram-positive and gram-negative bacteria and viruses. Antiseptic activity increases with increasing ethanol concentration.

    For disinfecting the skin, 70% solution is used, penetrating into deeper layers of the epidermis is better than 90-95%, It has a tanning effect on the skin and mucous membranes.

    It is a solvent for a number of medicinal products, as well as an extractant for a number of substances contained in medicinal plant raw materials.

    Pharmacokinetics:When used externally, it is absorbed from the surface of the skin and mucous membranes into the systemic circulation. In the metabolism of the drug, the isoenzyme CYP2E1 participates, the inductor of which it is.
    Indications:

    Treatment of the initial stages of diseases: furuncle, panaritium, mastitis; treatment of the hands of the surgeon (the methods of Fürbringer, Alfred), the operation field (including those with sensitivity to other antiseptics, in children and operations on areas with thin skin in adults - neck, face).

    Preservation of biological material, production of medicinal forms for, external use, tinctures, extracts.

    Contraindications:

    Hypersensitivity.

    Carefully:

    Pregnancy, lactation, children's age.

    Pregnancy and lactation:

    Use during pregnancy and lactation is permitted if the benefit to the mother exceeds the potential risk to the fetus and the baby.

    Dosing and Administration:

    Outer, in the form of lotions.

    70% solution is used to treat the surgical field and pre-surgical disinfection of the surgeon's hands, it is recommended to use a 40% solution for compresses and rubbing (to avoid burns).

    90% solution should be diluted to the required concentrations and used according to indications.

    Drugs prepared on the basis of ethanol are used in accordance with the instructions for the medical use of these dosage forms.

    Side effects:

    Allergic reactions, skin burns, hyperemia and soreness of the skin at the site of compression.

    When used externally, it is partially absorbed through the skin and mucous membranes and may have a resorptive general toxicity (central nervous system depression).
    Overdose:

    No data available.

    Interaction:

    No data available.

    Special instructions:

    In external application, ethanol is partially absorbed through the skin and mucous membranes, which must be taken into account when used in children, pregnant women and lactation.

    Effect on the ability to drive transp. cf. and fur:

    A medicinal preparation used as a solution for external use does not affect the ability to drive a car and other potentially dangerous mechanisms.For drugs based on ethanol, the influence on the ability to drive a vehicle and potentially other dangerous mechanisms is determined in accordance with the instructions for medical use for these dosage forms.

    Form release / dosage:

    Solution for external use and preparation of medicinal forms, 95%.

    Packaging:

    To 50, 100 ml in bottles of glass with a screw mouth, sealed with polyethylene plugs and screwed caps or aluminum roll-on caps with gaskets.

    Each vial with instructions for use is placed in a pack of cardboard.

    For 40 bottles of 100 ml or 70 bottles of 50 ml with an equal number of instructions for use are placed in a box of cardboard or a box of cardboard (for hospitals).

    For 40 bottles of 100 ml or 70 bottles of 50 ml with an equal number of instructions for use are placed in a box of cardboard or a box of cardboard (for production departments of pharmacies).

    By 10, 21.5, 31.5 liters in polyethylene cans (for production departments of pharmacies).

    By 10, 21.5, 31.5 liters in polyethylene cans. On the canister stick instruction for use (for hospitals).

    Storage conditions:

    In a well ukuporennoy packaging, away from sources of fire, in the dark place at a temperature of 12 to 15 ° C.

    In a place inaccessible to children.

    Shelf life:

    5 years.

    Do not use after the expiration date indicated on the package.

    Terms of leave from pharmacies:On prescription
    Registration number:LS-002102
    Date of registration:09.08.2011
    The owner of the registration certificate:MEDHIMPROM ПХФК, ОАО MEDHIMPROM ПХФК, ОАО Russia
    Manufacturer: & nbsp
    Information update date: & nbsp10.10.2015
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