Active substanceEthanolEthanol
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  • Dosage form: & nbspConcentrate for the preparation of solution for external use and preparation of dosage forms
    Composition:

    Composition per 1000 ml:

    Active substance: ethanol (ethyl alcohol 95%) - 1000 ml.

    Description:

    Transparent, colorless, mobile, volatile liquid with a characteristic alcohol smell.

    Pharmacotherapeutic group:antiseptic
    ATX: & nbsp

    D.08.A.X.08   Ethanol

    Pharmacodynamics:

    Antimicrobial agent, with external application has an antiseptic effect (denaturing proteins of microorganisms). It is active against gram-positive and gram-negative bacteria and viruses. Antiseptic activity increases with increasing ethanol concentration.

    For disinfecting the skin, 70% solution is used, penetrating deeper layers of the epidermis better than 90-95%, which has a tanning effect on the skin and mucous membranes.It is a solvent for a number of medicinal products, as well as an extractant for a number of substances contained in medicinal plant raw materials.

    Pharmacokinetics:

    When used externally, it is absorbed from the surface of the skin and mucous membranes into the systemic circulation. In the metabolism of the drug involved isoenzyme CYP2E1, the inductor of which it is.

    Indications:

    Treatment of the initial stages of diseases: furuncle, panaritium, mastitis; treatment of the hands of the surgeon (the methods of Fürbringer, Alfred), the operating field (including those with sensitivity to other antiseptics, in children and operations on areas with thin skin in adults - neck, face).

    Preservation of biological material, preparation of medicinal forms for external use, tinctures, extracts.

    Contraindications:

    Hypersensitivity.

    Carefully:

    Pregnancy, lactation, children's age.

    Pregnancy and lactation:

    Ethanol for external use is partially absorbed through the skin and mucous membranes, which should be taken into account when it is used in pregnant women and during lactation.

    Dosing and Administration:

    Outer, in the form of lotions.

    For compresses and wipes (in order to avoid burns), it is recommended to use a 40% solution in the initial stages of furuncles, panaricians, and mastitis.

    70% solution is used for preoperative disinfection of the surgeon's hands using the methods of Fürbringer, Alfred and the treatment of the operating field.

    95% The solution must be diluted to the required concentrations and used according to the indications.

    Drugs made on the basis of ethanol are used in accordance with the instructions for the medical use of these dosage forms.

    Side effects:

    Allergic reactions, skin burns, hyperemia and soreness of the skin at the site of compression.

    When used externally, it is partially absorbed through the skin and mucous membranes and may have a resorptive general toxicity (central nervous system depression).

    Overdose:

    When external application of an overdose was not noted.

    Interaction:

    Do not mix with other medicines that may decrease its specific activity.

    Special instructions:

    Ethanol for external use is partially absorbed through the skin and mucous membranes, which should be taken into account when it is used in children.

    Effect on the ability to drive transp. cf. and fur:

    When driving vehicles or potentially dangerous mechanisms, use the drug with caution because of the possible resorptive effect on the body.

    Form release / dosage:

    Concentrate for the preparation of solution for external use and preparation of medicinal forms, 95%.

    Packaging:

    To 50, 100 ml into bottles of glass.

    Each bottle, together with the instruction for use, is placed in a pack of cardboard box for consumer packaging.

    For 100 ml packaging, the text of the instructions for use can be applied to the pack.

    By 10, 20 liters in polyethylene cans ("For production departments of pharmacies," "For hospitals").

    The canister is additionally affixed with the instructions for use.

    Storage conditions:

    At a temperature of no higher than 25 ° C, in a well-ukuporennoy container, away from fire.

    Keep out of the reach of children.

    Shelf life:

    5 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:P N000146 / 01
    Date of registration:04.11.2011
    The owner of the registration certificate:MARBIOFARM, OJSC MARBIOFARM, OJSC Russia
    Manufacturer: & nbsp
    Representation: & nbspMARBIOFARM, OJSCMARBIOFARM, OJSC
    Information update date: & nbsp06.10.2015
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