Active substanceEthanolEthanol
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  • Dosage form: & nbspsolution for external use and preparation of dosage forms
    Composition:

    A mixture of alcohol and water, containing 95% of ethyl alcohol by volume.

    Description:Transparent, colorless, mobile liquid with a characteristic smell of alcohol.
    Pharmacotherapeutic group:antiseptic
    ATX: & nbsp

    D.08.A.X.08   Ethanol

    Pharmacodynamics:

    Antimicrobial, with local application has an antiseptic effect (denaturing proteins of microorganisms). It is active against gram-positive and gram-negative bacteria and viruses. Antiseptic activity increases with increasing ethanol concentration. To disinfect the skin, 70% solution is used, penetrating deeper layers of the epidermis better than 95%, which has a tanning effect on the skin and mucous membranes.

    It is a solvent for a number of drugs, as well as an extractant for a number of substances contained in medicinal plant raw materials.

    Pharmacokinetics:

    When used externally, it is absorbed from the surface of the skin and mucous membranes into the systemic circulation. In the metabolism of the drug involved isoenzyme CYP2E1. Inductor of which it is.

    Indications:

    Treatment of the initial stages of diseases: furuncle, panaritium, mastitis; treatment of the hands of the surgeon (the methods of Fürbringer, Alfred), the operating field (including those with sensitivity to other antiseptics, in children and operations on areas with thin skin in adults - neck, face).

    Preservation of biological material, production of medicinal forms for external use, tinctures, extracts.

    Contraindications:

    Hypersensitivity.

    Carefully:

    Pregnancy, lactation, children's age.

    Dosing and Administration:

    Outer, in the form of lotions. 70% solution is used to treat the surgical field and pre-surgical disinfection of the surgeon's hands, for the compresses and wipes (to avoid burns) it is recommended to use 40% solution, 95% solution should be diluted to the required concentrations and used according to indications.

    The drugs prepared on the basis of ethanol are used in accordance with the instructions for the medical use of these dosage forms.

    Side effects:

    Allergic reactions, skin burns, hyperemia and soreness of the skin at the site of compression.

    When used externally, it is partially absorbed through the skin and mucous membranes and may have a resorptive general toxicity (central nervous system depression).

    Special instructions:

    In external application, ethanol is partially absorbed through the skin and mucous membranes, which must be taken into account when used in children, pregnant women and lactation.

    Form release / dosage:

    Solution for external use, 95%.

    Packaging:

    To 25 ml, 50 ml, 100 ml into bottles of colorless or light-protective glass, sealed with polyethylene plugs or lids made of polyethylene or caps by aluminum or other closures.

    100 ml in polyethylene bottles complete with a cover with a control opening.

    3 l (2.43 kg), 5 l (4.05 kg), 8.10 kg (10 l), (16.20 kg) 20 l, (17.41 kg) 21.5 l, (25 , 51 kg) 31.5 l in cans of polymer materials or low-density polyethylene (for hospitals).

    Each label or canister is labeled with paper or a self-adhesive label.

    Each bottle, together with the instructions for use, is placed in a pack of cardboard.

    For 70 bottles with instruction on, the application is placed in a box of cardboard (for hospitals).

    Storage conditions:

    At a temperature of no higher than 25 ° C, in a sealed package, away from fire.

    Keep out of the reach of children.

    Shelf life:

    5 years.

    Do not use after the date indicated on the package.

    Terms of leave from pharmacies:On prescription
    Registration number:LSR-009896/09
    Date of registration:04.12.2009
    The owner of the registration certificate:NII OF MEDICINE AND STANDARDIZATION, LLC NII OF MEDICINE AND STANDARDIZATION, LLC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp08.10.2015
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