Active substanceEthanolEthanol
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  • Dosage form: & nbspRAster for external use and preparation of dosage forms.
    Composition:For 100 ml.

    Active substance: Ethanol (ethyl alcohol) 95%.

    Description:

    Colorless, transparent, mobile, volatile liquid with a characteristic alcohol smell.

    Pharmacotherapeutic group:antiseptic
    ATX: & nbsp

    D.08.A.X.08   Ethanol

    Pharmacodynamics:

    Antimicrobial, with local application has an antiseptic effect (denaturing proteins of microorganisms). It is active against gram-positive and gram-negative bacteria and viruses. Antiseptic activity increases with increasing ethanol concentration.

    For disinfecting the skin, 70% solution is used, penetrating deeper layers of the epidermis better than 90-95%, which has a tanning effect on the skin and mucous membranes.

    It is a solvent for a number of medicinal products, as well as an extractant for a number of substances contained in medicinal plant raw materials.

    Pharmacokinetics:

    When used externally, it is absorbed from the surface of the skin and mucous membranes into the systemic circulation. In the metabolism of the drug involved isoenzyme CYP2E1, the inductor of which it is.

    Indications:

    Treatment of the initial stages of diseases: furuncle, panaritium, mastitis; treatment of the hands of the surgeon (the methods of Fürbringer, Alfred), the operation field (including those with sensitivity to other antiseptics, in children and operations on areas with thin skin in adults - neck, face).

    Preservation of biological material, production of medicinal forms for external use, tinctures, extracts.

    Contraindications:

    Hypersensitivity.

    Carefully:

    Pregnancy, lactation, children's age.

    Pregnancy and lactation:

    Use during pregnancy and lactation is permitted if the benefit to the mother exceeds the potential risk to the fetus and the baby.

    Dosing and Administration:

    Outer, in the form of lotions, compresses, wipes.

    For the treatment of the operating field and the preoperative disinfection of the hands of the surgeon, 70% solution, for compresses and wipes (to avoid burns) it is recommended to use a 40% solution.

    95% of the drug should be diluted to the required concentrations.

    Drugs prepared on the basis of ethanol are used in accordance with the instructions for the medical use of these dosage forms.

    Side effects:

    Allergic reactions, skin burns, hyperemia and soreness of the skin at the site of compression.

    When used externally, it is partially absorbed through the skin and mucous membranes and may have a resorptive general toxicity (central nervous system depression).

    Overdose:

    No data available.

    Interaction:

    No data available.

    Special instructions:

    In external application, ethanol is partially absorbed through the skin and mucous membranes, which must be taken into account when used in children, pregnant women and lactation.

    Effect on the ability to drive transp. cf. and fur:

    In sensitive patients or with prolonged use, it is possible to reduce psychomotor reactions, which should be taken into account when driving vehicles, working with mechanisms, etc.

    For drugs prepared on the basis of ethanol, the influence on the ability to drive a car and potentially other dangerous mechanisms is determined in accordance withinstructions for medical use for these dosage forms.

    Form release / dosage:

    Concentrate for the preparation of solution for external use and preparation of medicinal forms, 95%.

    Packaging:

    To 25, 50, 100 ml in bottles of glass with a screw neck, sealed with polyethylene corks and screwed caps with polyethylene or aluminum caps.

    To 25, 50, 100 ml into bottles of polyethylene terephthalate for medicines.

    The vials are sealed with a screw cap of the polypropylene system "push and turn" with the control of the first opening or the cap of the first opening control system.

    For 25, 50, 100 ml in bottles of low-density polyethylene, complete with a cover with a control opening.

    To 25, 50, 100 ml in bottles of low-density polyethylene, complete with a cover with a control opening for medicines.

    Each vial with instructions for use is placed in a pack of cardboard.

    For 40 bottles of 100 ml or 70 bottles of 50 ml or 70 bottles of 25 ml with an equal number of instructions for use are placed in a box of cardboard or a box of cardboard corrugated (for hospitals).

    For 40 bottles of 100 ml or 70 bottles of 50 ml or 70 bottles of 25 ml with an equal number of instructions for use are placed in a box of cardboard or a box of cardboard corrugated (for production departments of pharmacies).

    For 40 bottles in a pack with instructions for 100 ml or 70 bottles in a pack of instruction on 50 ml or 70 bottles in a pack with instruction 25 ml each is placed in a box of cardboard or a box of cardboard corrugated.

    By 1, 3, 5, 10, 21.5, 31.5 liters in polyethylene cans of low-pressure polyethylene brand (for production departments of pharmacies).

    By 1, 3, 5, 10, 21.5, 31.5 liters in polyethylene cans of low-pressure polyethylene brand (for hospitals).

    For each bottle, canister, box, box label.

    On the canister (for hospitals) paste the instructions for use.

    Storage conditions:

    Store at a temperature of no higher than 25 ° C, in a well-ukuporennoy container, away from fire.

    In a place inaccessible to children.

    Shelf life:

    5 years.

    Do not use after the expiration date indicated on the package.

    Terms of leave from pharmacies:On prescription
    Registration number:LP-003811
    Date of registration:30.08.2016
    Expiration Date:30.08.2021
    The owner of the registration certificate:BIOFARMKOMBINAT, LLC BIOFARMKOMBINAT, LLC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp11.10.2016
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