Calcium gluconate - instructions for use, dose, side effects, contraindications

Excipients: potato starch - 16 mg, talc - 2.7 mg, polysorbate-80 (tween-80) - 6 mg, calcium stearate monohydrate (calcium stearate 1-water) - 5.3 mg.

Description:

Tablets are white, flat-cylindrical with a facet and a risk. Marble is allowed.

Pharmacotherapeutic group:Calcium-phosphorus exchange regulator

ATX: & nbsp

A.12.A.A.03 Calcium gluconate

A.12.A.A Calcium preparations

Pharmacodynamics:The preparation of calcium replenishes the deficiency of calcium ions necessary for the process of nerve impulse transmission, reduction of skeletal and smooth muscles, myocardial activity, bone formation, and blood coagulation.

Pharmacokinetics:Approximately 1 / 5-1 / 3 part of the orally administered drug is absorbed into the small intestine; this process depends on the presence of the vitamin D, pH, features of the diet and the presence of factors that can bind calcium ions. The absorption of calcium ions - increases with its deficiency and the use of a diet with a reduced content of ions calcium. About 20% is excreted by the kidneys, the rest (80%) by the intestine.

Indications:

Diseases, accompanied by hypocalcemia, increased permeability cell membranes (including blood vessels), impaired conduction of nerve impulses in muscle tissue.

Hypoparathyroidism (latent tetany, osteoporosis), metabolic disturbances of the vitamin D: rickets (spasmophilia, osteomalacia), hyperphosphatemia in patients with chronic renal insufficiency.

The increased need for calcium ions (pregnancy, lactation period, the period of increased body growth), insufficient calcium ions in food, a violation of its metabolism (in the postmenopausal period).

Enhanced excretion of calcium ions (prolonged bed rest, chronic diarrhea, secondary hypocalcemia, long-term use of diuretics and antiepileptic drugs, glucocorticosteroids).

Poisoning with magnesium salts, oxalic and fluoric acids and their soluble salts (in the interaction with calcium gluconate insoluble and non-toxic calcium oxalate and calcium fluoride are formed).

Hyperkaliemic form of paroxysmal myoplegia.

Contraindications:Increased individual sensitivity to the components of the drug. Hypercalcemia (calcium concentration should not exceed 12 mg% or 6 mEq / L); hypercalciuria, severe renal failure, propensity to thrombosis, nephrourolythiasis (calcium), sarcoidosis, simultaneous reception of cardiac glycosides, (risk of arrhythmias). Children's age up to 3 years.

Carefully:

Electrolyte disorders (risk of hypercalcemia), dehydration, diarrhea, malabsorption syndrome, chronic diseases of the gastrointestinal tract, calcium nephrourolythiasis in the anamnesis, chronic heart failure, ventricular fibrillation, widespread atherosclerosis, hypercoagulability.

Dosing and Administration:

Inside, before taking or after 1 - 1.5 h after eating (squeezed milk).

Grind before consumption.

Adults: 1 - 3 g (2 - 6 tablets) 2-3 times a day.

Children: 3 - 4 years, 2 tablets (1.0 g); 5-6 years for 2 - 3 tablets (1.0-1.5 g), 7-9 years for 3 - 4 tablets (1.5 - 2.0 g), 9-14 years on 4 - 6 tablets (2,0 - 3,0 g).

Take 2-3 times a day.

Side effects:

Allergic reactions, constipation, irritation of the mucous membrane of the gastrointestinal tract.

If any of the above at side effects instructions are aggravated, or you notice any other side effects not listed in the instructions, inform the doctor about it.

Overdose:

Symptoms: hypercalcemia (the concentration of total calcium in the serum is above 3 mmol / l).

Treatment: to eliminate it, 5-10 IU / kg / day calcitonin (diluting it in 0.5 L of 0.9% solution of sodium chloride). Duration of administration is 6 hours.

Interaction:

With simultaneous application from quinidine may inhibit intraventricular conduction and increase the toxicity of quinidine.

Forms insoluble complexes with antibiotics of the tetracycline series (reduces the antibacterial effect).

Slows the absorption of tetracyclines, digoxin, oral iron preparations (the interval between their methods should be at least 2 hours).

When combined with thiazide diuretics can increase hypercalcemia, reduce the effect of calcitonin in hypercalcemia. Reduces the bioavailability of phenytoin.Pharmaceutically incompatible with carbonates, salicylates, sulfates (forms insoluble or hardly soluble calcium salts).

Reduces the effect of blockers of slow calcium channels.

Special instructions:

Patients with minor hypercalciuria (total serum calcium in serum up to 3 mmol / l), with minor impairment of kidney function (creatinine clearance >45 ml / min) or a history of urolithiasis drug should be administered with caution and regularly monitor the level of excretion of calcium in the urine. Patients with a tendency to form concrements in the urine are encouraged to increase the amount of fluid consumed. If it is necessary to use simultaneously with other medicinal products, it is necessary to monitor the doctor.

Effect on the ability to drive transp. cf. and fur:

When administered orally in therapeutic doses calcium gluconate does not affect the ability to drive and perform work requiring increased attention.

Form release / dosage:

Tablets of 500 mg.

Packaging:

For 10 tablets in a contour non-cellular package of paper with a polymer coating.

For 10 tablets in a contour mesh package made of a polyvinylchloride film and aluminum foil or paper with a polymeric coating.

By 20, 25, 30, 40, 50, 60 tablets in cans of polymeric.

Each bank, or 1, 2, 3, 4, 5 contour non-jammed packages, or contour mesh packages together with the instruction for use, is placed in a bundle.

Banks polymeric, or contour non-cellular packages, or contour mesh packages with an equal number of instructions for use are placed in a bag of polyethylene film or a cardboard box.

Storage conditions:

In a dry place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

5 years.

Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-000802

Date of registration:03.10.2011

Expiration Date:Unlimited

The owner of the registration certificate:URALBIOFARM, OJSC URALBIOFARM, OJSC Russia

Manufacturer: & nbsp

URALBIOFARM, OJSC Russia

Information update date: & nbsp23.11.2017

Illustrated instructions

Instructions

Calcium gluconate (Calcium gluconate)