Calcium gluconate - instructions for use, dose, side effects, contraindications

The preparation of calcium ions replenishes the deficiency of calcium ions necessary for the process of nerve impulse transmission, reduction of skeletal and smooth muscles, myocardial activity, bone formation, and blood clotting.

Pharmacokinetics:

Approximately 1 / 5-1 / 3 part of the calcium gluconate taken up inside is absorbed in the small intestine; this process depends on the presence of the vitamin D, pH, features of the diet and the presence of factors that can bind calcium ions. The absorption of calcium ions increases with its deficiency and a diet with a reduced content of calcium ions. About 20% is excreted by the kidneys, the rest is the amount (80%) of the intestine (actively allocated by the wall of the terminal section of the gastrointestinal tract).

Indications:

Hypofunction of parathyroid glands (latent tetany, osteoporosis), a violation of vitamin metabolism D: rickets (spasmophilia, osteomalacia), hyperphosphatemia in patients with chronic renal insufficiency.

A condition accompanied by an increased need for calcium (a period of pregnancy, unbalanced and malnutrition). Chronic intoxication with salts of magnesium, oxalic and hydrofluoric acids and their soluble salts (when interacting with calcium gluconate forms insoluble salts and non-toxic calcium oxalate and calcium fluoride).

Hyperkaliemic form of paroxysmal myoplegia.

Contraindications:

Hypersensitivity to the components of the drug, hypercalcemia (calcium concentration should not exceed 12 mg% = 6 mEq / L), hypercalciuria, nephrourolythiasis (calcium), sarcoidosis, cardiac glycoside intoxication (risk of arrhythmias), severe renal failure, propensity to thrombosis. Children under 5 years.

Carefully:

Dehydration, electrolyte disorders (risk of hypercalcemia), diarrhea, malabsorption syndrome, minor hypercalciuria, mild chronic renal failure, chronic heart failure, prevalent atherosclerosis, hypercoagulability, chronic gastrointestinal tract diseases, calcium nephrourolythiasis in anamnesis.

Pregnancy and lactation:There is no information.

Dosing and Administration:

Inside, before or after 1-1.5 hours after eating (squeezed milk), adults -1-3 g (2-6 tablets) 2-3 times a day.

Children from 5 to 6 years - 2-3 tablets (1-1.5 g); from 7 to 9 years - 3-4 tablets (1.5-2 g); from 10 to 14 years - 4-6 tablets (2-3 g). Take 2-3 times a day.

Side effects:

Allergic reactions, constipation, irritation of the mucous membrane of the gastrointestinal tract, nausea, vomiting, diarrhea, pain in the upper abdomen.

Overdose:

Symptoms: hypercalcemia.

Treatment: to eliminate it, enter - 5-10 IU / kg / day calcitonin (diluting it in 0.5 L 0.9% solution of sodium chloride). Duration of administration 6 hours.

Interaction:

Reduces the pharmacological effects of blockers of "slow" calcium channels.

With simultaneous application with quinidine, it is possible to slow intraventricular conduction and increase the toxicity of quinidine. Slows down the absorption of tetracyclines, digoxin, oral iron preparations (the interval between their doses should be at least 2 h), when combined with thiazide diuretics can enhance hypercalcemia, reduce the effect of calcitonin in hypercalcemia, and reduce the bioavailability of phenytoin.

It is not recommended to use simultaneously with ethanol, carbonates, salicylates, sulfates (forms insoluble or hardly soluble calcium salts).

Special instructions:

Patients with minor hypercalciuria, with minor renal impairment or with a history of urolithiasis, should be administered with caution and should regularly monitor the level of calcium excretion in the urine. Patients with a tendency to form concrements in the urine are encouraged to increase the amount of fluid consumed.If it is necessary to use simultaneously with other medicinal products, it is necessary to monitor the doctor.

Effect on the ability to drive transp. cf. and fur:There is no information.

Form release / dosage:

Tablets 500 mg.

Packaging:

For 10 tablets in a contour non-cellular package of packaging paper.

For 10 tablets in a contour mesh box made of polyvinylchloride film and foil of aluminum printed lacquered or paper packaging.

By 2, 3 contour cell packs with tablets labeled "R" with instructions for use are placed in a pack of cardboard.

For 2, 3 contour squares with tablets without labeling "R" with instructions for use are placed in a pack of cardboard.

For 20 contour non-jawed or contiguous cell packs with tablets without the label "R" with an equal number of instructions for use are placed in a pack of cardboard.

Contour non-cellular or contiguous cell packs with tablets without "R" labeling with equal number of instructions for use are placed in a group package.

Storage conditions:

In a dry place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

5 years.

Do not use after the expiration date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LS-000651

Date of registration:01.06.2010 / 13.05.2015

Expiration Date:Unlimited

The owner of the registration certificate:UPDATE OF PFC, CJSC UPDATE OF PFC, CJSC Russia

Manufacturer: & nbsp

UPDATE, PFC CJSC Russia

Information update date: & nbsp23.11.2017

Illustrated instructions

Instructions

Calcium gluconate (Calcium gluconate)