During treatment, it is necessary to monitor the concentration of calcium in the blood serum.
The drug is injected deeply intramuscularly, or intravenously slowly (within 2-3 minutes), or drip, to exclude the possibility of local irritation or necrosis in case of getting the drug into the perivascular tissue.
Because of the risk of local irritation, intramuscular injections should be performed only if intravenous injection is not possible.
Intramuscular injections it is necessary to do deep enough in the muscle, preferably in the gluteal region.
Adults: deep intramuscularly, slowly intravenously (for 2-3 minutes) or drip 5-10 ml of 10% solution daily, every other day or 2 days (depending on the nature of the disease and the clinical condition of the patient). The subsequent doses are determined in accordance with the concentration of calcium in the blood serum.
Children under 18 years: the dose and mode of administration depend on the degree of development of hypocalcemia, the nature and severity of the symptoms.
Children, depending on age, the drug is administered in the following doses: up to 6 months - 0.1-1 ml; 7-12 months - 1-1.5 ml; 1-3 years -1.5-2 ml; 4-6 years - 2-2.5 ml; 7-14 years - 3-5 ml; over 14 years - doses, both for adults. The drug is injected every 2-3 days.
Children are not recommended to enter the drug intramuscularly because of the possible development of necrosis.
It is recommended only slow intravenous injection or intravenous infusion after dilution, in order to achieve sufficiently low rates of administration and to exclude the possibility of local irritation or necrosis with accidental ingestion of the drug into the perivascular tissue.
For intravenous infusion, the drug is diluted 1:10 to 10 mg / ml with the following infusion solutions: 0.9% sodium chloride solution or 5% glucose solution. The rate of intravenous administration should not exceed 50 mg of calcium gluconate per minute.
The solution before the introduction is warmed to body temperature. The syringe for the administration of calcium gluconate should not contain ethanol residues (in order to avoid the precipitation of calcium gluconate).