Hexicon® (Hexicon®)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceChlorhexidineChlorhexidine
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    • Dosage form: & nbspsolution for local and external use
    Composition:

    Active substance: chlorhexidine bigluconate 20% - 0.25 ml, excipient: purified water - up to 100 ml.

    Description:

    Colorless transparent or slightly opalescent liquid without odor.

    Pharmacotherapeutic group:Antiseptic
    ATX: & nbsp

    D.08.A.C.02   Chlorhexidine

    G.01.A.X   Other antiseptics and antimicrobials for the treatment of gynecological diseases

    Pharmacodynamics:

    Hexicon ® is an antiseptic drug that is active against gram-positive and gram-negative bacteria (Treponema pallidum, Chlamidia spp., Ureaplasma spp., Neisseria gonorrhoeae, Gardnerella vaginalis, Bacteroides fragilis); protozoa (Trichomonas vaginalis); viruses (Herpes virus). Keeps activity (albeit somewhat lowered) in the presence of blood, pus.

    Pharmacokinetics:Virtually not absorbed from the digestive tract. After accidental ingestion of 300 mg, the maximum concentration is reached after 30 minutes and is 0.206 μg / L. It is produced mainly with a fecal mass (90%), less than 1% is excreted by the kidneys.
    Indications:

    Prevention of sexually transmitted infections (chlamydia, ureaplasmosis, trichomoniasis, gonorrhea, syphilis, genital herpes, etc.).

    Disinfection of purulent wounds, infected burn surfaces; treatment of infections of the skin and mucous membranes in surgery, obstetrics-gynecology, urology (urethritis, urethroprostatitis), dentistry (rinsing and irrigation - gingivitis, stomatitis, aphthae, paradontitis, alveolitis).

    Contraindications:

    Hypersensitivity to the components of the drug, dermatitis, allergic reactions.

    Carefully:Childhood.
    Dosing and Administration:

    To prevent sexually transmitted infections, hexicon® is effective if it is applied no later than 2 hours after sexual intercourse.

    The contents of the vial with a nozzle insert into the urethra for men (2-3 ml), for women (1-2 ml) and for the vagina (5-10 ml) and hold for 2-3 minutes.

    Treate the skin with the internal surfaces of the hips, pubic area, genitals. After the procedure, do not urinate for two hours.

    Complex treatment of urethritis and urethroprostatitis is carried out by injecting into the urethra 2-3 ml of a solution of Gexikon ® 1-2 times a day, the course - 10 days. The procedures are scheduled every other day.

    Solution Hexicon ® is also used in the form of irrigation, rinses and applications - 5-10 ml of the solution is applied to the affected surface of the skin or mucous membranes with an exposure of 1-3 minutes 2-3 times per day (on a tampon or by irrigation).

    Side effects:

    Allergic reactions, itching, dry skin, dermatitis, stickiness of the skin of hands (within 3-5 minutes), photosensitization. In the treatment of gingivitis - staining the enamel of the teeth, deposition of tartar, a violation of taste.

    Interaction:

    It is not recommended simultaneous application with iodine.

    Hexicon ® is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps. The presence of soap can inactivate chlorhexidine, so before using the drug, soap residues should be thoroughly rinsed.

    Ethanol enhances the effectiveness of the drug.

    Special instructions:

    Avoid getting the drug inside the wound in patients with open craniocerebral trauma, spinal cord injuries, perforation of the tympanic membrane.

    If the solution gets on the mucous membranes of the eye, they should be washed quickly and thoroughly with water.

    The contact of hypochlorite bleaching substances on tissues that previously were in contact with the containing chlorhexidine drugs, can contribute to the appearance of brown spots on them.

    The bactericidal effect is enhanced with an increase in temperature. At a temperature above 100 ° C the drug is partially decomposed.

    Form release / dosage:Hexicon® solution for external use 0,05%.
    Packaging:

    10 ml, 50 ml, 70 ml, 100 ml, 150 ml, 200 ml, 250 ml and 500 ml in polyethylene bottles with a polymer packing; Vial with instructions for medical use in the pack.

    Storage conditions:In a place protected from light and inaccessible to children, at a temperature of no higher than 25 ° C.
    Shelf life:2 years. Do not use the product after the expiry date printed on the package.
    Terms of leave from pharmacies:Without recipe
    Registration number:P N001901 / 02
    Date of registration:29.09.2009 / 14.08.2013
    Expiration Date:Unlimited
    The owner of the registration certificate:NIZHFARM, JSC NIZHFARM, JSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp17.03.2017
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