Chlorhexidine - instructions for use, dose, side effects, contraindications

Antiseptic. Effective against vegetative forms of Gram-positive and Gram-negative bacteria (Treponema pallidum, Neisseria gonorrhoeae, Chlamydia spp., Ureaplasma spp., Bacteroides fragilis); protozoa (Trichomonas vaginalis); viruses Herpes-virus (Herpes simplex 2 type), as well as yeast and dermatophytes. Preserves activity (although somewhat decreased) in the presence of blood, pus. On bacterial spores, it only acts with increased temperature.

Pharmacokinetics:

With local and external application is almost not absorbed.

Indications:

As a therapeutic and prophylactic for various infections.

For topical application: Trichomonas colpitis, cervical erosion, vulvar pruritus, prevention of sexually transmitted infections (chlamydia, ureaplasmosis, trichomoniasis, gonorrhea, syphilis, genital herpes).

Disinfection of purulent wounds, infected burn surfaces; disinfection of the skin (scrapes, cracks), treatment of infections of the skin and mucous membranes in surgery, obstetrics and gynecology, urology (urethritis, urethroprostatitis), dentistry (rinse and irrigation - gingivitis, stomatitis, aphthae, periodontitis, alveolitis).

Contraindications:

Hypersensitivity to the components of the drug, dermatitis.

Carefully:

Children's age, pregnancy, lactation.

Pregnancy and lactation:

Use during pregnancy and breastfeeding is possible if the intended benefit to the mother exceeds the potential risk to the fetus or child.

Dosing and Administration:

Outwardly. Locally. It is used in the form of irrigation and applications - 5-10 ml of the drug is applied to the affected surface of the skin or mucous membranes with an exposure of 1-3 minutes 2-3 times per day (on a tampon or by irrigation).

For the prevention of sexually transmitted diseases, the drug is effective if it is used no later than 2 hours after sexual intercourse.

Enter 0.05% chlorhexidine solution into the urethra: men (2-3 ml), women (1-2 ml) and in the vagina (5-10 ml) for 2-3 min. Treat the skin of the inner surfaces of the hips, pubic area, genitals. After the procedure, do not urinate for 2 hours.

Complex treatment of urethritis and urethroprostatitis is carried out by injecting into the urethra 2-3 ml 1 -2 times a day, the course - 10 days, the procedure is prescribed every other day.

0.05% aqueous solution of chlorhexidine is applied in the form of rinsing 2-3 times a day.

Side effects:

Allergic reactions (skin rash), dry skin, itching, dermatitis, stickiness of the skin of the hands (within 3-5 minutes), photosensitization.

In the treatment of gingivitis - staining the enamel of the teeth, deposition of tartar, a violation of taste.

If any of the above at side effects are worsened, or you notice any other side effects not listed in the instructions, inform the doctor about it.

Overdose:

Currently, no cases of overdose with external and topical application have been reported; when accidentally ingested, it is practically not absorbed (gastric lavage should be done). If necessary, symptomatic therapy is performed.

Interaction:

It is used in a neutral environment. At a pH greater than 8 precipitates.

It is not recommended simultaneous use with iodine-containing drugs if they are administered intravaginally.

It is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose), and soaps.

The presence of soap can inactivate chlorhexidine, so before using the drug, soap residues should be thoroughly washed off.

Compatible with preparations containing a cationic group (benzalkonium chloride, cetrimonium chloride).

Ethanol enhances the effectiveness of the drug.

Special instructions:

Avoid getting the drug inside the wound in patients with open craniocerebral trauma, spinal cord injuries, perforation of the tympanic membrane.

In case of contact with the eye mucous membrane, rinse thoroughly and thoroughly with water.

The ingestion of hypochlorite bleaching substances on tissues that previously were in contact with the containing chlorhexidine drugs, can contribute to the appearance of brown spots on them.

The bactericidal effect is enhanced with an increase in temperature. At a temperature above 100 ° C the drug is partially decomposed.

Effect on the ability to drive transp. cf. and fur:

Not studied.

Form release / dosage:Solution for external and local application 0,05%.

Packaging:

By 100, 250, 500, 1000, 1500 or 2000 ml in polymeric containers made of polyvinylchloride for single-use solutions.

Each container is placed in a bag of polyethylene or polyethylene-polyamide film. Containers in bags are placed in a box of corrugated cardboard with gaskets: 50, 75 pieces (100 ml), 24, 36 pieces (250 ml), 12, 18 pieces (500 ml), 6, 9 pieces (1000 ml ), 4 pieces (1500 ml), 4 pieces (2000 ml).In the container box, instructions are put on the medical use of the drug and guidelines for the use of polymer containers at the rate of 1 piece per 6 containers (for treatment and prophylactic institutions).

Storage conditions:

In the dark place at a temperature of no higher than 25 ° C.

Keep out of the reach of children. It is allowed to freeze the drug provided the container is kept tight.

Shelf life:

2 years. Do not use after the expiry date printed on the package. After the expiry date of the drug, unused containers should be carefully opened, the contents drained into the drain.

Terms of leave from pharmacies:For hospitals

Registration number:LP-002259

Date of registration:01.10.2013

The owner of the registration certificate:MEDSINTEZ FACTORY, LTD. MEDSINTEZ FACTORY, LTD. Russia

Manufacturer: & nbsp

MEDSINTEZ FACTORY, LTD. Russia

Information update date: & nbsp26.09.2015

Illustrated instructions

Instructions

Chlorhexidine (Chlorhexidine)