Active substanceChlorhexidineChlorhexidine
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  • Dosage form: & nbspsolution for local and external use
    Composition:

    Active substance: Chlorhexidine bigluconate solution 20% - 2.5 ml (equivalent to 500 mg chlorhexidine bigluconate)

    Excipient: purified water - up to 1000 ml

    Description:Colorless transparent or slightly opalescent liquid without odor.
    Pharmacotherapeutic group:Antiseptic.
    ATX: & nbsp

    D.08.A.C.02   Chlorhexidine

    G.01.A.X   Other antiseptics and antimicrobials for the treatment of gynecological diseases

    Indications:

    As a therapeutic and prophylactic agent for various infections, for antiseptic treatment and disinfection.

    0,05% solution: prevention of sexually transmitted infections (chlamydia, ureaplasmosis, trichomoniasis, gonorrhea, syphilis, genital herpes - application no later than 2 hours after sexual intercourse); disinfection of the skin (scrapes, cracks). Purulent wounds, infected burns, bacterial and fungal diseases of the skin and mucous membranes in dentistry (rinsings and irrigation - gingivitis, stomatitis, aphthae, paradontitis, alveolysis). Surgery, urology, obstetrics-gynecology.

    Contraindications:Hypersensitivity, dermatitis, allergic reactions.
    Carefully:

    Children under 12 years old, pregnancy, lactation.

    Pregnancy and lactation:

    The use of chlorhexidine during pregnancy and during breastfeeding is possible after consulting a doctor. In pregnancy and during breastfeeding apply only if the intended benefit to the mother exceeds the potential risk to the fetus and the baby.

    Dosing and Administration:

    Chlorhexidine as a preventive and therapeutic agent is used externally and locally. 0.05% aqueous solution - 5-10 ml of the solution is applied to the affected surface of the skin or mucous membranes with an exposure of 1 to 3 minutes 2-3 times per day (on a tampon or by irrigation).

    For prevention of sexually transmitted diseases chlorhexidine bigluconate It is effective if it is applied no later than 2 hours after sexual intercourse. The contents of the vial with the help of a nozzle to enter the urethra for men (2-3 ml), for women (1-2 ml) and for the vagina (5-10 ml) for 2-3 min. Treat the skin of the inner surfaces of the hips, pubic area, genitals. After the procedure, do not urinate for 2 hours.

    Comprehensive treatment of urethritis and urethroprostatitis by g by injecting into the urethra 2-3 ml of 0.05% chlorhexidine solution 1-2 times a day, the course is 10 days, the procedures are prescribed every other day.

    0.05% aqueous solution is used as a rinse 2-3 times a day.

    Side effects:

    Allergic reactions (skin rash), dry skin, itching, dermatitis, stickiness of the skin of the hands (within 3-5 minutes), photosensitivity.

    In the treatment of gingivitis - dyeing of teeth, deposition of tartar, a violation of taste.

    If any of the side effects listed in the manual are aggravated, or if you notice any other side effects not listed in the instructions,inform the doctor about it.

    Overdose:

    Treatment: with accidental ingestion is almost not absorbed (should be done by rinsing the stomach using milk, raw egg, gelatin). If necessary, symptomatic therapy is performed.

    Cases of overdose with external or topical application are not known.
    Interaction:

    It is used in a neutral environment; at pH 5-8, the difference in activity is small; at a pH of more than 8 - precipitate. The use of hard water slightly reduces bactericidal properties.

    Pharmaceutically incompatible with soap, alkalis and other anionic compounds (colloids, gum arabic, carboxymethyl cellulose).

    Compatible with preparations containing a cationic group (benzalkonium chloride, cetrimonium bromide).

    Ethanol enhances the effectiveness of the drug.

    Special instructions:

    In patients with an open craniocerebral trauma, spinal cord injuries, perforation of the tympanic membrane, one should avoid getting to the surface of the brain, the meninges and the drum cavity.

    In case of contact with the mucous membranes of the eye, they should be washed quickly and thoroughly with water.

    The contact of hypochlorite bleaching substances on tissues that previously were in contact with the containing chlorhexidine drugs, can contribute to the appearance of brown spots on them.

    At a temperature above 100 ° C the drug is partially decomposed.

    It is not recommended simultaneous application with iodine.

    Effect on the ability to drive transp. cf. and fur:

    Not studied.

    Form release / dosage:Solution for local and external use.
    Packaging:

    To 50, 100 ml of the drug in bottles made of dark glass, sealed with stoppers, plastic caps and caps screwed on or caps are cork-screwed.

    25 ml, 50 ml, 70 ml. 100 ml, 200 ml in bottles of polyethylene with a polymer packing.

    25 ml, 50 ml, 100 ml in bottles of polyethylene terephthalate with the means of closure or polyethylene, capped with polypropylene caps.

    By 1, 3, 5, 10, 20 liters in polyethylene cans. (For hospitals).

    Each vial with instructions for use is placed in a pack of cardboard.

    It is possible to put the full text of the instruction on the pack.

    Packaging of vials without a pack together with an equal number of instructions for use in group packaging is allowed.
    Storage conditions:

    AT protected from light at a temperature of no higher than 25 ° C. Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use after the expiry date printed on the package.
    Terms of leave from pharmacies:Without recipe
    Registration number:LP-001555
    Date of registration:01.03.2012
    The owner of the registration certificate:KEMEROVSKAYA PHARMACEUTICAL FACTORY, OJSC KEMEROVSKAYA PHARMACEUTICAL FACTORY, OJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp26.09.2015
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