Chlorhexidine bigluconate - instructions for use, dose, side effects, contraindications

Antiseptic, shows bactericidal action (against Gram-positive and Gram-negative bacteria) - at a temperature of 22 ° C and exposure for 1 minute; fungicidal action - at a temperature of 22 ° C and exposure for 10 minutes; virucidal action (against lipophilic viruses). Effective against Gram-positive and Gram-negative bacteria - Treponema spp., Neisseria gonorrhoeae, Trichomonas spp., Chlamydia spp., Ureaplasma spp. Stable, after the treatment of the skin is stored on it in a certain amount, sufficient for the manifestation of bactericidal effect. Keeps activity (although somewhat reduced) in the presence of blood, pus, various secrets and organic substances. Very rarely causes allergic reactions, skin and tissue irritation, does not have a damaging effect on objects made of glass, plastics and metals.

Pharmacokinetics:With local and external application is almost not absorbed.

Indications:

Prevention of infections,sexually transmitted diseases (chlamydia, ureaplasmosis, trichomoniasis, gonorrhea, syphilis, genital herpes - application no later than 2 hours after sexual intercourse); disinfection of the skin (scrapes, cracks). Purulent wounds, infected burns, bacterial and fungal diseases of the skin and mucous membranes in surgery, urology, obstetrics and gynecology, dentistry (gingivitis, stomatitis, aphthae, periodontitis, alveolitis).

Contraindications:Hypersensitivity, dermatitis.

Carefully:childhood.

Pregnancy and lactation:

In pregnancy and during breastfeeding apply only if the intended benefit to the mother exceeds the potential risk to the fetus and the baby.

Dosing and Administration:Locally. Outwardly. 5-10 ml of the solution is applied to the affected surface of the skin or mucous membranes with an exposure of 1-3 minutes 2-3 times per day (on a tampon or by irrigation).

For the prevention of sexually transmitted diseases, the drug is effective; if it is applied no later than 2 hours after sexual intercourse. The contents of the vial with the help of a dropper cap should be introduced into the urethra for men (2-3 ml), for women (1-2 ml) and for the vagina (5-10 ml) for 2-3 min.To treat the skin of internal surfaces, thighs, pubic area, genitals. After the procedure, do not urinate for 2 hours. Complex treatment of urethritis and urethroprostatitis is carried out by injecting into the urethra 2-3 ml of chlorhexidine solution 1-2 times a day, the course -10 days, the procedure is prescribed every other day.

Rinse solution for topical administration is usually administered 2-3 times a day.

Side effects:

Allergic reactions (skin rash), dry skin, itching, dermatitis, photosensitization, tooth enamel staining, scaling, taste disturbance.

Overdose:

In case of accidental ingestion, it is practically not absorbed (it is necessary to rinse the stomach using milk, raw egg, gelatin). If necessary, symptomatic therapy is performed.

Interaction:

It is used in a neutral environment. At a pH of more than 8, a precipitate forms. The drug is not used in combination with anionic compounds, including soap. The drug is incompatible with carbonates, chlorides, phosphates, borates, sulfates and citrates. Chlorhexidine Bigluconate increases the sensitivity of microorganisms to the action of kanamycin, neomycin, cephalosporins, chloramphenicol.Ethyl alcohol enhances the bactericidal action of the drug.

Special instructions:

In patients with open craniocerebral trauma, spinal cord injuries, perforation of the tympanic membrane, one should avoid getting onto the surface of the brain, the meninges and the cavity of the inner ear.

In case of contact with the mucous membranes of the eyes, they should be washed quickly and thoroughly with water.

At a temperature above 100 ° C the drug is partially decomposed. It is not recommended simultaneous application with iodine.

Effect on the ability to drive transp. cf. and fur:

no data.

Form release / dosage:

Solution for local and external use 0,05%.

Packaging:

For 100 ml of the drug in the bottles of orange glass, sealed with plastic stoppers and screwed caps.

For 80 and 100 ml of the drug in polymer bottles with nozzles-droppers and caps screwed from polymeric materials.

Each vial with instructions for use is placed in a pack of cardboard.

It is allowed to pack bottles together with an equal number of instructions for use in group packaging.

Storage conditions:

In the dark place at a temperature of no higher than 25 ° C. Keep out of the reach of children.

Shelf life:

2 years. Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-001347

Date of registration:12.12.2011

The owner of the registration certificate:TULA PHARMACEUTICAL FACTORY, LTD. TULA PHARMACEUTICAL FACTORY, LTD. Russia

Manufacturer: & nbsp

TULA PHARMACEUTICAL FACTORY, LTD. Russia

Information update date: & nbsp26.09.2015

Illustrated instructions

Instructions

Chlorhexidine Bigluconate (Chlorhexidine bigluconate)