Active substanceChlorhexidineChlorhexidine
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  • Dosage form: & nbspVaginal suppositories
    Composition:

    One suppository contains: active substance - chlorhexidine bigluconate solution of 20% (0.08 g) corresponds to chlorhexidine bigluconate-16 mg.

    Excipients: macrogol-1500 - 2,299 g, macrogol-400 - 0,121 g.

    Description:

    Suppositories white or white with a yellowish hue of color, torpedo-shaped. Marble surface is allowed.

    Pharmacotherapeutic group:Antiseptic.
    ATX: & nbsp

    D.08.A.C.02   Chlorhexidine

    G.01.A.X   Other antiseptics and antimicrobials for the treatment of gynecological diseases

    Pharmacodynamics:

    Chlorhexidine is an antiseptic drug for local (intravaginal) use, is active against simple, gram-positive and gram-negative bacteria, viruses, including against Treponema pallidum, Chlamydia spp., Ureaplasma spp. Neisseria gonorrhoeae. Trichomonas vaginalis, Gardnerella vaginalis, Bacteroides fragilis, Herpes simplex 2 type. Some strains are slightly sensitive to the drug Pseudomonas spp., Proteus spp., and also resistant to acid-fast forms of bacteria, spores of bacteria. Chlorhexidine does not interfere with the functional activity of lactobacilli. Pharmacokinetics

    Systemic absorption with intravaginal application is insignificant.

    Indications:

    Prevention of sexually transmitted infections (chlamydia, ureaplasmosis, trichomoniasis, gonorrhea, syphilis, genital herpes and others).

    Prevention of infectious and inflammatory complications in obstetrics and gynecology (before operative treatment of gynecological diseases, before childbirth and abortion, before and after installation of the intrauterine device (IUD), before and after diathermocoagulation of the cervix, before intrauterine tests).

    Treatment of bacterial vaginosis, colpitis (including nonspecific, mixed, trichomonads).

    Contraindications:Hypersensitivity to the components of the drug, children's age.
    Carefully:

    Pregnancy, lactation.

    Pregnancy and lactation:

    The use of the drug during pregnancy and during lactation is possible if the intended benefit to the mother exceeds the potential risk to the fetus and the baby.

    Dosing and Administration:

    Intravaginal. Preliminarily releasing the suppository from the contour cell package, insert it into the vagina in the supine position on the back.

    For treatment - 1 suppository 2 times a day for 7-10 days. If necessary, it is possible to extend the course of treatment to 20 days.

    For prevention sexually transmitted infections - 1 suppository not later than 2 hours after sexual intercourse.

    Side effects:

    Extremely rare (less than 0.1% of cases) are allergic reactions, itching of the skin, after the drug is withdrawn.

    Overdose:

    At present, no cases of drug overdose have been reported.

    Interaction:

    It is not recommended simultaneous use with iodine-containing drugs if they are administered intravaginally.

    Chlorhexidine is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps if they are administered intravaginally. Toilet of external genitalia does not affect the efficacy and tolerability of vaginal suppositories Chlorhexidine, since the drug is administered intravaginally.

    Special instructions:

    Chlorhexidine retains activity (albeit somewhat lowered) in the presence of blood, pus.

    Form release / dosage:

    Vaginal suppositories 16 mg.

    Packaging:

    5 suppositories per contour cell packaging made of polyvinyl chloride film.

    2 contour mesh packs together with instructions for use are placed in a pack of cardboard.

    Storage conditions:

    In dry, dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    2 years. Do not use after the expiration date.

    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-007184/10
    Date of registration:27.07.2010
    The owner of the registration certificate:BIOCHEMIST, OJSC BIOCHEMIST, OJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp26.09.2015
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