Chlorhexidine-SF - instructions for use, dose, side effects, contraindications

Antiseptic. It shows bactericidal action at a temperature of 22 ° C and exposure for 1 min; fungicidal action at a temperature of 22 ° C and exposure for 10 min; virucidal action (against lipophilic viruses). Effective against vegetative Gram-positive and Gram-negative bacteria (Treponema pallidum, Neisseria gonorrhoeae, Chlamydia spp., Ureaplasma spp., Bacteroides fragile); protozoa (Trichomonas vaginalis); viruses and fungi. Stable, after the treatment of the skin is stored on it in a certain amount, sufficient for the manifestation of bactericidal effect. Keeps activity (although somewhat reduced) in the presence of blood, pus, various secrets and organic substances. On bacterial spores acts only at elevated temperature.

Pharmacokinetics:

With local and external application is almost not absorbed. The drug is not absorbed into the systemic circulation. After accidental ingestion of C_m_Oh is achieved after 30 minutes and is 0.206 μg / l. It is excreted mainly by the intestine (90%), less than 1% is excreted by the kidneys.

Indications:

As a therapeutic and prophylactic for various infections, for aseptic treatment and disinfection.

Prevention of sexually transmitted infections (chlamydia, ureaplasmosis, trichomoniasis, gonorrhea, syphilis, genital herpes).

Disinfection of purulent wounds, infected burn surfaces; disinfection of the skin (scrapes, cracks), treatment of infections of the skin and mucous membranes in surgery, obstetrics and gynecology, urology (urethritis, urethroprostatitis), dentistry (rinse and irrigation - gingivitis, stomatitis, aphthae, periodontitis, alveolitis).

Contraindications:

Hypersensitivity to chlorhexidine, dermatitis.

Carefully:

Children's age, pregnancy, the period of breastfeeding.

Pregnancy and lactation:

Application in pregnancy and during breastfeeding is possible if the intended benefit to the mother exceeds the potential risk to the fetus or child.

Before using the drug, if you are pregnant, or suspect that you might be pregnant, or plan a pregnancy, you should consult your doctor during breastfeeding.

Dosing and Administration:

Locally. Outwardly.

It is used in the form of irrigation and applications - 5-10 ml of the drug is applied to the affected surface of the skin or mucous membranes with an exposure of 1-3 minutes 2-3 times per day (on a tampon or by irrigation).

For the prevention of sexually transmitted diseases, the drug is effective if it is used no later than 2 hours after sexual intercourse.

Introduce chlorhexidine solution into the urethra: men (2-3 ml), women (1-2 ml) and vagina (5-10 ml) for 2-3 min. Treat the skin of the inner surfaces of the hips, pubic area, genitals. After the procedure, do not urinate for 2 hours. Complex treatment of urethritis and ureoprostatitis is carried out by injecting into the urethra 2-3 ml 1-2 times a day, a course of 10 days, the procedures are prescribed every other day.

Rinse solution for topical administration is usually administered 2-3 times a day.

If there is no improvement after treatment, or the symptoms worsen, or new symptoms appear, it is necessary to consult a doctor. Use the drug only according to the indications, the method of administration and the doses indicated in the instructions.

Side effects:

Allergic reactions (skin rash), dry skin, itching, dermatitis, stickiness of the skin of the hands (within 3-5 minutes), photosensitization. Severe allergic reactions, including anaphylaxis.In the treatment of gingivitis - staining the enamel of the teeth, deposition of tartar, a violation of taste.

If any of the side effects listed in the manual are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor.

Overdose:

Currently, no cases of overdose with external and topical application have been reported; with accidental ingestion is almost not absorbed (should be done by rinsing the stomach using milk, raw egg, gelatin). If necessary, symptomatic therapy is performed.

Interaction:

It is used in a neutral environment. At a pH of more than 8, a precipitate forms.

It is not recommended simultaneous use with iodine-containing drugs if they are administered intravaginally.

It is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose), and soaps.

The presence of soap can inactivate chlorhexidine, so before using the drug, soap residues should be thoroughly washed off.

Compatible with preparations containing a cationic group (benzalkonium chloride, centrimony bromide).

If you use the above or other medicines (including OTC drugs) before using the drug, consult your doctor.

Special instructions:

Avoid getting the drug inside the wound in patients with open craniocerebral trauma, spinal cord injuries, perforation of the tympanic membrane.

In case of contact with the eye mucous membrane, rinse thoroughly and thoroughly with water.

When hypochlorous bleaching substances get on tissues that were previously in contact with containing chlorhexidine drugs, can contribute to the appearance of brown spots on them.

The bactericidal effect is enhanced with an increase in temperature. At a temperature above 100 ° C the drug is partially decomposed.

Effect on the ability to drive transp. cf. and fur:

Not studied.

Form release / dosage:

Solution for local and external use 0,02%.

Packaging:

For 500 ml of the drug in polyethylene bottles with Euro-cap.

By 500, 1000 or 2000 ml into containers of multi-layer polymer film.

A single container is packaged in an individual polymer bag made of a polypropylene or polyethylene film or without an individual polymer bag.

1 bottle with the drug and instructions for medical use are placed in a pack of cardboard.

For 16 bottles with an equal number of instructions for medical use are placed in a box of corrugated cardboard (for hospitals).

For 18 500 ml containers or 6 1000 ml containers or 4 2000 ml containers, each of which is packed in a polymer bag or without a polymer bag, with equal number of instructions for medical use, they are placed in a box of corrugated cardboard (for hospitals) .

Storage conditions:

Store in a dark place at a temperature of no higher than 25⁰ FROM.

Keep out of the reach of children.

Shelf life:

2 years. Do not use after the expiration date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LP-004426

Date of registration:23.08.2017

Expiration Date:23.08.2022

The owner of the registration certificate:Sphera-Pharm, OOOSphera-Pharm, OOO Russia

Manufacturer: & nbsp

Sphera-Pharm, OOO Russia

Information update date: & nbsp12.09.2017

Illustrated instructions

Instructions

Chlorhexidine-SF (Chlorhexidine-SF)