Active substanceSodium chlorideSodium chloride
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  • Dosage form: & nbspsolution for infusions
    Composition:

    Active substance: sodium chloride - 9 g.

    Excipient: water for injection - up to 1 liter.

    Theoretical osmolarity is 308 mOsm / l.

    Description:

    clear, colorless liquid.

    Pharmacotherapeutic group:rehydrating agent.
    ATX: & nbsp

    B.05.C.B.01   Sodium chloride

    B.05.X.A.03   Sodium chloride

    Pharmacodynamics:

    Has a detoxifying and rehydrating effect. Replenishes sodium deficiency with various pathological conditions of the body and temporarilyincreases the volume of fluid circulating in the vessels.

    Pharmacokinetics:

    Quickly excreted by the kidneys unchanged.

    Indications:

    Isotonic sodium chloride solution is used to dissolve drugs, as well as with large losses of extracellular fluid or insufficient intake (toxic dyspepsia, cholera, diarrhea, indomitable vomiting, extensive burns with severe exudation, etc.), hypochloremia and hyponatremia with dehydration, intestinal obstruction , intoxication, for washing wounds, eyes, nasal mucosa, for regional perfusion together with heparin, antitumor drugs and other drugs.

    Contraindications:

    Hypernatremia, acidosis, hyperchloremia, hypokalemia, extracellular hyperhydration, circulatory disorders, threatening edema of the brain and lungs, cerebral edema, pulmonary edema, acute left ventricular failure, concomitant assignment glucocorticosteroids in large doses.

    Carefully:

    Carefully: decompensated chronic heart failure, chronic renal failure (oligo-anuria).

    Pregnancy and lactation:

    No information.

    Dosing and Administration:

    Isotonic sodium chloride solution for infusion is administered intravenously (usually capeliao), subcutaneously, rectally or topically (to rinse the wounds, eyes, mucous membrane of the nasal cavity), to moisten the dressing.

    Before administration, the solution is heated to 36-38 ° C. The dose is determined depending on the loss of body fluids, sodium ions and chlorine - an average of 1000 ml / day. With large losses of fluid and severe intoxication, it is possible to administer up to 3000, ml / day. The rate of administration is 540 ml / h (180 cal / min): if necessary, the rate of administration is increased.

    Children with a marked decrease in blood pressure on the background of dehydration (before determining the laboratory parameters) are administered 20-30 ml / kg. In the future, the dosage regimen is adjusted depending on the laboratory parameters.

    Side effects:

    The introduction of large volumes of isotonic sodium chloride solution can lead to chloride acidosis and hyperhydratonia, as well as hypokalemia.

    Overdose:not described
    Interaction:

    Compatible with colloid hemodynamic blood substitutes (mutual enhancement of the effect).

    When mixed with other drugs, you need to visually check for compatibility.

    Special instructions:

    With long-term administration of large doses of isotonic sodium chloride solution, it is necessary to monitor the acid-base state and electrolytes in blood plasma and urine.

    With significant dehydration with the impossibility of intravenous administration is administered subcutaneously or rectally.

    Effect on the ability to drive transp. cf. and fur:not described
    Form release / dosage:

    Solution for infusion 0.9%.

    Packaging:

    For 100, 200, 250, 400, 500 ml in glass bottles.

    For 100, 200, 250, 400, 500 ml into polymeric bottles with a capacity of 100, 250, 500 ml, respectively.

    For 100, 250, 500 ml in polymer containers.

    Each polyvinyl chloride container is placed in a bag of polyethylene film.

    1 bottle with instructions for medical use of the drug in a pack of cardboard.

    For 28 bottles with a capacity of 100 or 250 ml or 15 bottles with a capacity of 450 or 500 ml with the appropriate number of instructions for medical use of the drug placed in boxes of cardboard (for hospitals).

    A container with a capacity of 100 ml or 34 containers (a container bag) of 250 ml capacity or 22 containers (a container bag) of 500 ml capacity with appropriate number of instructions for medical use is placed in boxes of cardboard (for hospitals) .

    Storage conditions:

    At a temperature not higher than 25 ° C, out of the reach of children.

    In the event of a change in the color of the preparation or the appearance of a suspension, the solutions are not suitable for use.

    Freezing the drug under the condition that the bottle is not leaking is not a contraindication to its use.

    HAchaItMachivaemstudt inner surface of the oathell is not a contraindication to the use of the drug.
    Shelf life:2 years. Do not use after expiry date.
    Terms of leave from pharmacies:On prescription
    Registration number:P N001119 / 01
    Date of registration:28.10.2011
    Expiration Date:Unlimited
    The owner of the registration certificate:ESKOM NPK, OAO ESKOM NPK, OAO Russia
    Manufacturer: & nbsp
    Information update date: & nbsp23.06.2014
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