Sodium chloride - instructions for use, dose, side effects, contraindications

Has detoxification and rehydration action. Replenishes the deficiency of sodium ions in various pathological conditions.0.9% solution of sodium chloride is isotonic with human plasma and is therefore rapidly eliminated from the vascular bed, only temporarily increasing the volume of circulating blood (effectiveness with blood loss and shock is insufficient).

Pharmacokinetics:

The concentration of sodium ions is 142 mmol / l (plasma) and 145 mmol / l (interstitial fluid), the chloride concentration is 101 mmol / l (interstitial fluid). It is excreted by the kidneys.

Indications:

- Large losses of extracellular fluid or insufficient intake (toxic dyspepsia, cholera, diarrhea, "indomitable" vomiting, extensive burns with severe exudation, etc.);

- hypochloraemia and ginonatremia with dehydration;

- intestinal obstruction;

- intoxication;

- washing of wounds, eyes, mucous membrane of the nasal cavity;

- dissolution and dilution of medicinal products;

- moistening of the dressing material.

Contraindications:

Hypernatremia, acidosis, hyperchloremia, hypokalemia, extracellular gynahydration; circulatory disorders that threaten edema of the brain and lungs; edema of the brain, pulmonary edema, acute left ventricular failure, concomitant administration of glucocorticosteroids in large doses.

Carefully:

Decompensated chronic cardiac failure, chronic renal failure (oligonuria).

Dosing and Administration:

Intravenously, drip; subcutaneously, rectally, place, externally.

Intravenous drip introduction: before administration, the sodium chloride solution is heated to 36-38 ° C. The dose of the administered solution is determined depending on the loss of body fluids, sodium and chloride ions and on average is 1 l / day. With large losses of fluid and severe intoxication, administration up to 3 l / day is possible. The rate of administration is 540 ml / h; if necessary, the rate of administration is increased.

Children with a marked decrease in blood pressure on the background of dehydration (before determining the laboratory parameters) are administered 20-30 ml / kg. In the future, the dosage regimen is adjusted depending on the laboratory parameters. With prolonged administration of large doses of 0.9% solution of sodium chloride, it is necessary to monitor the electrolytes in plasma and urine.

0,9% solution of sodium chloride is used to wash wounds, eyes, mucous membrane of the nasal cavity, moistening the dressing.

In enemas - up to 3 liters / day 0.9% solution.

Side effects:

Acidosis, hyperhydration, hypokalemia.

Interaction:

When mixed with other drugs, it is necessary to visually check compatibility (nevertheless, invisible and therapeutic incompatibility is possible).

Special instructions:

It is necessary to control the acid-base state and electrolytes.

Form release / dosage:

Solution for infusions 0,9%.

Packaging:

100 ml, 200 ml, 400 ml in glass bottles with a capacity of 100 ml, 250 ml, 450 ml, sealed with rubber stoppers, crimped with aluminum or combined caps.

For hospitals:

- 48 bottles of 100 ml, 24 bottles of 200 ml, 12 bottles of 400 ml with an equal number of instructions for use in a box of corrugated cardboard;

- from 1 to 48 bottles of 100 ml, from 1 to 24 bottles of 200 ml, from 1 to 12 bottles of 400 ml with an equal number of instructions for use in a box of corrugated cardboard.

100 ml, 200 ml, 250 ml, 400 ml, 500 ml, 1000 ml into polymeric containers of a polyolefin film with one or two ports.

For hospitals:

- 72 containers of 100 ml, 30 containers of 200 ml or 250 ml, 21 containers of 400 ml or 500 ml, 10 containers of 1000 ml in bags of polyethylene or polypropylene film with an equal number of instructions for use in a box of corrugated cardboard;

- from 1 to 72 containers of 100 ml,from 1 to 30 containers of 200 ml or 250 ml, from 1 to 21 containers of 400 ml or 500 ml, from 1 to 10 containers of 1000 ml in bags of a film of polyethylene or polypropylene with an equal number of instructions for use in a box of corrugated cardboard.

Stacking of containers without packages is allowed.

Storage conditions:

At a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:2 years. Do not use after expiry date.

Terms of leave from pharmacies:On prescription

Registration number:P N003523 / 01

Date of registration:21.11.2008 / 28.02.2018

Expiration Date:Unlimited

The owner of the registration certificate:KRASFARMA, JSC KRASFARMA, JSC Russia

Manufacturer: & nbsp

KRASFARMA, JSC Russia

Information update date: & nbsp15.06.2018

Illustrated instructions

Instructions

Sodium chloride (Sodium chloride)