Active substanceSodium chlorideSodium chloride
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  • Dosage form: & nbspsolution for infusions
    Composition:

    Active substances:

    Sodium chloride 9 g

    Excipients:

    Water for injection up to 1 liter

    0.1 M hydrochloric acid solution acid to pH 5.0-7.5

    0.1 M sodium solution hydroxide to pH 5.0 to 7.5

    Theoretical osmolarity - 308 mOsm / l

    Description:Transparent colorless liquid.
    Pharmacotherapeutic group:Rehydrating agent
    ATX: & nbsp

    B.05.C.B.01   Sodium chloride

    B.05.X.A.03   Sodium chloride

    Pharmacodynamics:Has a detoxifying and rehydrating effect.Replenishes sodium deficiency in various pathological conditions of the body and temporarily increases the volume of fluid circulating in the vessels.
    Pharmacokinetics:Quickly excreted by the kidneys unchanged.
    Indications:

    Isotonic sodium chloride solutionRead is used for large sweatextracellular fluid or notsufficient intake (toxicitydyspepsia, cholera, diarrhea, indomitable vomiting, extensive burns with strong exudation, etc.), hypochloremia and hyponatremia with dehydrationliving, intestinal impassablein toxicity, for the regionperfusion together with heparin, antitumor and other lemedicinal means.

    Contraindications:Hypernatremia, acidosis, hyperchloremia, hypokalemia, extracellular hyperhydration, circulatory disorders threatening edema of the brain and lungs, cerebral edema, pulmonary edema, acute left ventricular failure, concomitant administration of glucocorticosteroids in large doses.
    Carefully:
    Decompensated chronic heart failure, chronic renal failure (oligo-anuria).
    Pregnancy and lactation:Absolute contraindication to the use of the drug during pregnancy and breastfeeding is not present. The drug is recommended to be used under the supervision of a doctor, carefully evaluating the "benefit / risk" ratio.
    Dosing and Administration:

    Isotonic sodium chloride solution for infusions is administered intravenously (usually drip).

    Before administration, the solution is heated to 36-38 ° C. The dose is determined depending on the loss of body fluids, sodium ions and chlorine. The average dose of the drug is 1000 ml / day. With large fluid loss and severe intoxication, administration of up to 3000 ml / day is possible. The rate of administration is 540 ml / h (180 cap / min); if necessary, the rate of administration is increased.

    Children with a marked decrease in blood pressure on the background of dehydration (before determining the laboratory parameters) are administered 20-30 ml / kg of body weight. In the future, the dosage regimen is adjusted depending on the laboratory parameters.

    Side effects:The introduction of large volumes of isotonic sodium chloride solution can lead to chloride acidosis and hyperhydration, as well as to hypokalemia.
    Interaction:

    Compatible with colloid hemodynamic blood substitutes (mutual enhancement of the effect).

    When mixed with other drugs, you need to visually check for compatibility.

    Special instructions:

    With prolonged administration of large doses of isotonic sodium chloride solution, it is necessary to monitor the acid-base state and electrolytes in blood plasma and urine.

    For the preparation in a polymeric container, freezing is permissible during transportation of the solution in the event that the integrity of the container is preserved. Check the integrity of the container before use.

    In the event of a change in the color of the preparation or the appearance of a suspension, the solution is not suitable for use.

    For the preparation in a glass bottle, the non-wetting of the inner surface of the bottle is not a contraindication to the use of the preparation.

    Effect on the ability to drive transp. cf. and fur:Does not affect the ability to drive vehicles and engage in potentially hazardous activities that require increased concentrationtion.
    Form release / dosage:

    Solution for infusions, 0,9%.

    Packaging:

    For 100, 200, 400 ml of the preparation in bottles of glass.

    1 bottle with instructions for the use of the drug in a pack of cardboard.

    It is allowed to put the text of the instruction on the use of the printing method on the pack without instructions on the use of the medicinal product.

    For hospitals: 36 bottles without a 100 ml bottle, or 15, 28 bottles of 200 ml, or 15 400 ml bottles, along with instructions for the use of the drug in an amount corresponding to the number of primary packaging units in a cardboard box.

    For 100, 200, 250, 300, 400, 500, 1000, 2000, 3000 ml of the preparation in polymeric containers. The container is placed in a bag of polyethylene film.

    For hospitals, the polymer container is not packaged in a bag of polymer film.

    44 containers of 100 ml,

    32 containers with a volume of 200 ml,

    28 containers of 250 ml,

    20 containers of 300 ml volume,

    16 containers of 400 ml,

    12 containers of 500 ml,

    6 containers with a volume of 1000 ml,

    4 containers of 2000 ml,

    2 containers of 3000 ml in bags of polyethylene film

    together with the guidelines for the use of polymer containers with an infusion solution are placed in a box of cardboard.

    For hospitals: polymeric containers without insertion into a polyethylene film bag are packed in a cardboard box together with a guide for the use of polymer containers with an infusion solution.

    If the text of the instruction on the use of the medicinal product is not printed on the surface of the polymeric container or polyethylene film bag, instructions for the use of the preparation in the amount corresponding to the number of polymer containers are put in the box.

    Storage conditions:

    Store in dry place at a temperature not higher 25 ° C. Keep out of the reach of deth place.

    Shelf life:

    3 years. Do not apply at the expiry date.

    Terms of leave from pharmacies:On prescription
    Registration number:LSR-005263/07
    Date of registration:25.12.2007 / 12.02.2018
    Expiration Date:Unlimited
    The owner of the registration certificate:MOSFARM, LLCMOSFARM, LLC
    Manufacturer: & nbsp
    Information update date: & nbsp15.06.2018
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