Active substanceSodium chlorideSodium chloride
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  • Dosage form: & nbspsolution for infusions
    Composition:

    Active substance: sodium chloride - 9.0 g,

    adjuvant: water for injection - up to 1 liter.

    Theoretical osmolarity is 308 mOsm / l.

    Description:

    Transparent colorless liquid.

    Pharmacotherapeutic group:Rehydrating agent
    ATX: & nbsp

    B.05.C.B.01   Sodium chloride

    B.05.X.A.03   Sodium chloride

    Pharmacodynamics:

    Has a detoxifying and rehydrating effect. Replenishes sodium deficiency in various pathological conditions of the body and temporarily increases the volume of fluid circulating in the vessels.

    Pharmacokinetics:

    Quickly excreted by the kidneys unchanged.

    Indications:

    Isotonic sodium chloride solution is used to dissolve drugs, as well as with large losses of extracellular fluid or insufficient intake (toxic dyspepsia, cholera, diarrhea, indomitable vomiting, extensive burns with severe exudation, etc.), hypochloremia and hyponatremia with dehydration, intestinal obstruction , intoxication, for washing wounds, eyes, nasal mucosa, for regional perfusion together with heparin, antitumor drugs and other drugs.

    Contraindications:

    Hypernatremia, acidosis, hyperchloremia, hypokalemia, extracellular hyperhydration, circulatory disorders threatening edema of the brain and lungs, cerebral edema, pulmonary edema, acute left ventricular failure, concomitant administration of glucocorticosteroids in large doses.

    Carefully:

    Decompensated chronic heart failure, chronic renal failure (oligo-anuria).

    Pregnancy and lactation:

    No information.

    Dosing and Administration:

    Isotonic sodium chloride solution for infusions is administered intravenously (usually drip), subcutaneously, rectally or topically (for washing wounds, eyes, mucous membrane of the nasal cavity), to moisten the dressing.

    Before administration, the solution is heated to 36-38 ° C. The dose is determined depending on the loss of body fluids, sodium ions and chlorine - an average of 1000 ml / day. With large fluid loss and severe intoxication, administration of up to 3000 ml / day is possible. The rate of administration is 540 ml / h (180 cap / min); if necessary, the rate of administration is increased.

    Children with a marked decrease in blood pressure on the background of dehydration (before determining the laboratory parameters) are administered 20-30 ml / kg. In the future, the dosage regimen is adjusted depending on the laboratory parameters.

    Side effects:

    The introduction of large volumes of isotonic sodium chloride solution can lead to chloride acidosis and hyperhydration, as well as to hypokalemia.

    Interaction:

    Compatible with colloid hemodynamic blood substitutes (mutual enhancement of the effect).

    When mixed with other drugs, you need to visually check for compatibility.

    Special instructions:

    With prolonged administration of large doses of isotonic sodium chloride solution it is necessary to monitor the acid-base state and electrolytes in blood plasma and urine.

    With significant dehydration with the impossibility of intravenous administration is administered subcutaneously or rectally.

    Form release / dosage:

    Solution for infusion 0.9%.

    Packaging:

    100 ml, 200 ml, 250 ml, 400 ml, 500 ml or 1000 ml in polymeric containers for infusion solutions of PVC with one or with an additional injection port.

    100 ml, 200 ml, 250 ml, 400 ml, 500 ml or 1000 ml into polymeric containers for infusion solutions of polypropylene.

    100 ml, 200 ml, 250 ml, 400 ml, 500 ml or 1000 ml into polyolefin containers for infusion solutions.

    100 ml, 200 ml, 250 ml, 400 ml, 500 ml or 1000 ml in self-falling bottles made of polypropylene.

    One container is packed in a bag of polyethylene film or a multilayer film.

    For each package, stick the label self-adhesive with instructions for use or 60 packs with 100 ml containers,

    30 packs with 200 ml containers,

    for 24 bags with 250 ml containers,

    15 bags with 400 ml containers,

    for 12 bags with 500 ml containers,

    6 packages eachcontainers of 1000 ml with an equal number of instructions for use are placed in a group package in a box of corrugated cardboard.

    1 bottle together with the instruction for medical use is placed in a pack of cardboard.

    Storage conditions:

    Store at temperatures between 0 and 25 ° C. Keep out of the reach of children. Freezing of the drug during transportation (provided the container is tight) is not a contraindication to the use. After freezing, keep containers or vials in transport containers at room temperature until completely thawed, before shaking, mix the solution in a container or vial with shaking.

    Shelf life:2 years. Do not use after the expiration date.
    Terms of leave from pharmacies:On prescription
    Registration number:LSR-002671/08
    Date of registration:10.04.2008 / 13.04.2018
    Expiration Date:Unlimited
    The owner of the registration certificate:AVEKSIMA, JSC AVEKSIMA, JSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp16.06.2018
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