Sodium chloride - instructions for use, dose, side effects, contraindications

Has a detoxifying and rehydrating effect. Replenishes sodium deficiency in various pathological conditions of the body and temporarily increases the volume of fluid circulating in the vessels.

Pharmacokinetics:

Quickly excreted by the kidneys unchanged.

Indications:

Isotonic sodium chloride solution is used to dissolve drugs, as well as with large losses of extracellular fluid or insufficient intake (toxic dyspepsia, cholera, diarrhea, indomitable vomiting, extensive burns with severe exudation, etc.), hypochloremia and hyponatremia with dehydration, intestinal obstruction , intoxication, for washing wounds, eyes, nasal mucosa, for regional perfusion together with heparin, antitumor drugs and other drugs.

Contraindications:

Hypernatremia, acidosis, hyperchloremia, hypokalemia, extracellular hyperhydration, circulatory disorders threatening edema of the brain and lungs, cerebral edema, pulmonary edema, acute left ventricular failure, concomitant administration of glucocorticosteroids in large doses.

Carefully:

Decompensated chronic cardiac insufficiency, chronic renal failure (oligo-anuria).

Pregnancy and lactation:

No information.

Dosing and Administration:

Isotonic sodium chloride solution for infusions is administered intravenously (usually drip), subcutaneously, rectally or topically (for washing wounds, eyes, mucous membrane of the nasal cavity), to moisten the dressing.

Before administration, the solution is heated to 36-38 ° C. The dose is determined depending on the loss of body fluids, sodium ions and chlorine - an average of 1000 ml / day. With large fluid loss and severe intoxication, administration of up to 3000 ml / day is possible. The rate of administration is 540 ml / h (180 cap / min); if necessary, the rate of administration is increased.

Children with a marked decrease in blood pressure on the background of dehydration (before determining laboratory parameters) are administered 20-30 ml / kg. In the future, the dosage regimen is adjusted depending on the laboratory parameters.

Side effects:

The introduction of large volumes of isotonic sodium chloride solution can lead to chloride acidosis and hyperhydration, as well as to hypokalemia.

Interaction:

Compatible with colloid hemodynamic blood substitutes (mutual enhancement of the effect).

When mixed with other drugs, you need to visually check for compatibility.

Special instructions:

With prolonged administration of large doses of isotonic sodium solution chloride, it is necessary to monitor the acid-base state and electrolytes in blood plasma and urine.

With significant dehydration when intravenous administration is administered subcutaneously or rectally.

Form release / dosage:

Solution for infusion 0.9%.

Packaging:

200 ml or 400 ml in glass bottles for blood, transfusion and infusion preparations.

1 bottle with instructions for use in a pack of cardboard.

For 20, 24 or 28 bottles with a capacity of 250 ml or 15 bottles with a capacity of 450 ml with an equal number of instructions for use in a cardboard box with partitions (for hospitals).

Storage conditions:

At a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Note. Freezing the drug, provided that the bottle is not leaking, and also the non-wetting of the inner surface of its wall are not grounds for refusing to use it.

Shelf life:

3 years. Do not use after the expiration date indicated on the label.

Terms of leave from pharmacies:For hospitals

Registration number:LSR-005359/07

Date of registration:26.12.2007 / 03.09.2014

Expiration Date:Unlimited

The owner of the registration certificate:Kursk Biofactory - BIOK, FKPKursk Biofactory - BIOK, FKP Russia

Manufacturer: & nbsp

Kursk Biofactory - BIOK, FKP Russia

Information update date: & nbsp15.06.2018

Illustrated instructions

Instructions

Sodium chloride (Sodium chloride)