Sodium chloride - instructions for use, dose, side effects, contraindications

Sodium chloride has a detoxifying and rehydrating effect.Replenishes sodium deficiency in various pathological conditions of the body. 0.9% solution of sodium chloride is isotonic with human blood plasma, so it is quickly removed from the vascular bed, only temporarily increasing the volume of fluid circulating in the vessels.

Pharmacokinetics:Quickly excreted by the kidneys unchanged.

Indications:

Plasmonisotonic substitution of a liquid, gypsumbad weatherRheumatic alkalosis, hyponatremia with dehydration, intoxication.

Contraindications:

Hypernatremia, hyperchloremia, hypokalemia, extracellular hyperhydration, circulatory disorders threatening edema of the brain and lungs, cerebral edema, pulmonary edema, decompensated heart failure, concomitant high-dose corticosteroid therapy, chronic renal failure and conditions that can cause sodium retention, hypervolemia and edema (central and peripheral), such as: primary aldosteronism and secondary aldosteronism, caused, for example, by arterial hypertension throat, congestive heart failure, liver disease (including cirrhosis) and kidneys (including stenosis of the renal arteries and nephrosclerosis),pre-eclampsia; contraindications to the drugs added to the solution.

Carefully:

Chronic heart failure, acidosis, arterial hypertension, peripheral edema, toxicosis of pregnant women.

Pregnancy and lactation:

The drug can be used during pregnancy and during breastfeeding. Data on the use of the drug during pregnancy and during breastfeeding is not enough.

Dosing and Administration:

Intravenously. Before the introduction, the preparation is heated to 36 ° C - 38 ° C.

Doses, speed and duration of application are selected individually depending on the indication for use, age, body weight, the patient's condition and concomitant therapy, as well as on the effectiveness of treatment in terms of general symptoms and laboratory indicators.

For adults: an average of 1000 ml / day, with large losses of fluid and intoxications (toxic dyspepsia, cholera), it is possible to administer up to 3000 ml / day. The rate of intravenous injection is 540 ml / h (180 drops / min), if necessary, the rate of administration is increased.

For children: with shock dehydration (without determining laboratory parameters) 20-30 mg / kg / day are administered.In the future, the dosage regimen is adjusted depending on the laboratory parameters.

Side effects:

On the part of the circulatory system: acidosis, hyperhydration, hypokalemia.

From the immune system: hypersensitivity reactions or infusion reactions, including arterial hypotension, pyrexia, tremor, chills, urticaria, rash, itching.

General disorders and disorders at the site of administration: reactions at the injection site, such as erythema at the injection site, hemorrhage / hematoma at the injection site, burning sensation, urticaria at the injection site.

When using the drug as a base solution for other drugs, the likelihood of unwanted reactions is determined by the properties of these drugs. In this case, if unwanted reactions appear, you should suspend the solution, assess the patient's condition, take adequate measures and save the remaining solution for analysis, if necessary.

Overdose:

Overdosing can lead to chloride acidosis, hyperhydration, increase the excretion of potassium from the body. When combined with other drugs, complaints with excessive administration are most often associated with the properties of added drugs.

Overdose Symptoms: vomiting, diarrhea, abdominal cramps, thirst, reduced salivation and lacrimation, sweating, fever, tachycardia, increased blood pressure, renal failure, peripheral edema, pulmonary edema, respiratory arrest, headache, dizziness, restlessness, irritability, weakness , muscle cramps and muscle stiffness, generalized convulsions, coma.

Treatment: symptomatic. When symptoms of an overdose occur, the drug should be discontinued.

Interaction:

Compatible with colloid hemodynamic blood substitutes (mutual enhancement of the effect).

When mixed with other drugs, you need to visually check for compatibility.

Special instructions:

The solution can be used only if it is transparent, without visible inclusions, and its packaging is not broken.

With prolonged administration of large doses of the drug, it is necessary to monitor the acid-base state and the concentration of electrolytes in blood plasma and urine.

If there is significant dehydration when intravenous injection is not possible, the drug is administered subcutaneously or rectally.

Effect on the ability to drive transp. cf. and fur:

The drug has no effect on the ability to control mechanisms and the car.

Form release / dosage:

Solution for infusion 0.9%

Packaging:

For 250 or 500 ml in a bottle of low-density polyethylene, closed with a lid of polypropylene. Each label is labeled self-adhesive and placed in a bag of polypropylene BOPP film.

24 bottles of 250 ml together with an equal number of instructions for use are placed in a box of corrugated cardboard (for hospitals).

25 bottles of 500 ml together with an equal number of instructions for use are placed in a box of corrugated cardboard (for hospitals).

Storage conditions:

Store at a temperature not exceeding 30 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after the expiration date.

Terms of leave from pharmacies:For hospitals

Registration number:LP-002677

Date of registration:24.10.2014 / 08.08.2016

Expiration Date:24.10.2019

The owner of the registration certificate:Akulayf Helskea Pvt. Ltd.Akulayf Helskea Pvt. Ltd. India

Manufacturer: & nbsp

Aculife Healthcare Pvt Ltd. India

Representation: & nbspCompany AlkemiCompany Alkemi

Information update date: & nbsp15.06.2018

Illustrated instructions

Instructions

Sodium chloride (Sodium chloride)