Inside.The drug is used during or immediately after a meal and is washed down with a sufficient amount of water.
The dosage regimen is set individually, depending on the severity of the disease.
In the treatment of infections of the skin and mucous membranes caused by Herpes simplex 1 and 2 types. Adults: the drug is prescribed at 200 mg 5 times a day for 5 days with 4 hour intervals during the day and with an 8-hour interval at night. In more severe cases of the disease, the course of treatment can be extended to the doctor's prescription up to 10 days. As part of complex therapy with severe immunodeficiency, including in the expanded clinical picture of HIV infections (including early clinical manifestations of HIV infection and the stage of AIDS); after bone marrow transplantation, 400 mg 5 times a day are prescribed.
To prevent recurrence of infections caused by viruses Herpes simplex 1 and 2 types, patients with normal immune status and relapse of the disease are prescribed 200 mg 4 times a day every 6 hours, the duration of the course is from 6 to 12 months.
To prevent infections caused by viruses Herpes simplex 1 and 2 types, adults with immunodeficiency, the drug is recommended to appoint 200 mg 4 times a day every 6 hours, the maximum dose is up to 400 mg of acyclovir 5 times a day, depending on the severity of the infection.
Children: to treat infection caused by Herpes simplex and prevention of this infection in patients with weakened immune defenses, children older than 3 years receive the same dose as adults.
In the treatment of infections caused by Varicella zoster:
Adults: 800 mg 5 times a day every 4 hours in the afternoon and with an 8-hour interval at night. Duration of treatment 7-10 days.
Children: with chicken pox it is prescribed 20 mg / kg 4 times a day for 5 days (maximum single dose 800 mg), children from 3 to 6 years: 400 mg 4 times a day, over 6 years: 800 mg 4 once a day for 5 days.
In the treatment of infections caused by Herpes zoster, adults are prescribed 800 mg 4 times a day every 6 hours for 5 days.
In patients with impaired renal function:
In the treatment and prevention of infections caused by Herpes simplex, in patients with creatinine clearance less than 10 ml / min dose should be reduced to 200 mg 2 times a day, with 12-hour intervals.
In the treatment of infections caused by Varicella zoster, in patients with creatinine clearance less than 10 ml / min, it is recommended to reduce the dose of the drug to 800 mg twice a day with 12 racial intervals; with the clearance of creatinine 10-25 ml / min is prescribed 800 mg 3 times a day with 8-hour intervals.