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Treatment should be started as soon as possible, immediately after the appearance of the first symptoms of the disease.
It is established individually depending on the severity of the disease.
In the treatment of infections of the skin and mucous membranes caused by Herpes simplex type I and II adults and children over 3 years of age the drug is prescribed 200 mg 5 times a day for 5 days with 4 hour intervals during the day and with an 8-hour interval at night. In more severe cases, the course of treatment can be extended to the doctor's prescription. As part of complex therapy with severe immunodeficiency, including when the clinical picture of HIV infection (including, early clinical manifestations of HIV infection and stage of AIDS), after the implantation of the bone marrow is prescribed 400 mg 5 times a day.
To prevent recurrence of infections caused by viruses Herpes simplex type I and II, patients with normal immune status and relapse of the disease are prescribed 200 mg 4 times a day every 6 hours.
To prevent infections caused by viruses Herpes simplex type I and II, adults and children older than 3 years with immunodeficiency, the drug is recommended to appoint 200 mg 4 times a day every 6 hours, the maximum dose - up to 400 mg of acyclovir 5 times a day, depending on the severity of the infection.
In the treatment of infections caused by Varicella zoster, adults are prescribed 800 mg 5 times a day every 4 hours in the afternoon and with an 8-hour interval at night. Duration of treatment 7-10 days. Children older than 3 years are prescribed 20 mg / kg 4 times a day for 5 days, children with a body weight of more than 40 kg, the drug is prescribed in the same dosage as adults.
In the treatment of infections caused by Herpes zoster, adults are prescribed 800 mg 4 times a day every 6 hours for 5 days.
In patients with impaired renal function:
In the treatment and prevention of infections caused by Herpes simplex, in patients with creatinine clearance less than 10 ml / min, the dosage of the drug should be reduced to 200 mg twice a day with 12-hour intervals.
In the treatment of infections caused by Varicella zoster, in patients with creatinine clearance less than 10 ml / min, it is recommended to reduce the dosage of the drug to 800 mg 2 times a day with 12-hour intervals; with a creatinine clearance of up to 25 ml / min, 800 mg 3 times a day with 8 hour intervals is prescribed.
The drug is taken during or immediately after a meal and is washed down with a sufficient amount of water.