Virollex - instructions for use, dose, side effects, contraindications

Acyclovir is active against Herpes simplex 1 and 2 types, virus Varicella zoster, the Epstein-Barr virus and cytomegaloviruses. Thymidine kinase virus-infected cells through a series of consecutive reactions actively converts acyclovir in mono-, di- and triphosphate of acyclovir. The latter interacts with the viral DNA polymerase and is embedded in DNA, which is synthesized for new viruses. Thus, "defective" viral DNA is formed, which leads to suppression of replication of new generations of viruses.

Pharmacokinetics:

With repeated use of the cream, systemic absorption is minimal.

Indications:

Infections of the skin and mucous membranes caused by the virus Herpes simplex types 1 and 2, including herpes lips and genital herpes.

Contraindications:Hypersensitivity to acyclovir or to any other component of the drug.

Carefully:

Pregnancy and lactation.

Pregnancy and lactation:

Adequate and strictly controlled clinical studies of the safety of the drug during pregnancy were not conducted. The application is indicated only in cases where the intended use for the mother exceeds the potential risk to the fetus.

Dosing and Administration:

Outwardly. The drug is recommended to apply 5 times a day (approximately every 4 hours) a thin layer on the affected and bordering skin areas. Duration of treatment is not less than 5 days. In the absence of healing, treatment can be continued up to 10 days. If the symptoms persist for more than 10 days, you should consult your doctor.

The cream is applied either with a cotton swab or with clean hands to avoid additional infection of the affected areas.

Side effects:

Some patients may experience short-term redness, skin rashes, vulvitis, tenderness, itching, flaking, burning or tingling in the application areas. In very rare cases, the development of allergic dermatitis, more often associated with the reaction to auxiliary substances.

There are isolated reports of cases of edema of Quincke with topical application of acyclovir drugs.

Interaction:

When external application of interaction with other drugs is not revealed.

Special instructions:

To achieve maximum therapeutic effect, it is necessary to apply the drug already at the first signs of the disease (burning, itching, tingling, sensation of tension and redness).

When pronounced manifestations of herpes lips is recommended to consult a doctor.

The cream is not recommended to be applied to the mucous membranes of the mouth and eyes, as it is possible to develop local inflammation.

In the treatment of genital herpes should consult with a doctor. It is recommended to avoid sexual contact or use condoms, since the use of acyclovir does not prevent the transmission of the virus to partners.

Patients with immunodeficiency states in the treatment of any infectious diseases should follow the recommendations of the doctor.

Form release / dosage:Cream for external use 5%.

Packaging:

5 g of the drug in an aluminum tube with a screwed plastic cover. The tube is packed in a cardboard pack together with instructions for use.

Storage conditions:

Store at temperatures between 8 ° C and 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use the drug after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:П N014287 / 02

Date of registration:19.05.2008 / 15.01.2013

Expiration Date:Unlimited

Date of cancellation:2015-12-14

The owner of the registration certificate:KRKA, dd, Novo mesto, AOKRKA, dd, Novo mesto, AO

Manufacturer: & nbsp

KRKA, d.d. Slovenia

Representation: & nbspKRKA, dd, Novo mesto, AOKRKA, dd, Novo mesto, AO

Information update date: & nbsp20.02.2017

Illustrated instructions

Instructions

Virollex (Virolex)