Intravenously drip.
The concentration and dose of the dextrose solution is determined by several factors, including age, body weight and general condition of the patients.
5% solution injected at a maximum rate of up to 7 ml (150 cap / min) (400 ml / h); the maximum daily intake for adults is 2 liters;
10% glucose solution - up to 60 cap / min (3 ml / min); the maximum daily intake for adults is 1 liter;
20% glucose solution - up to 30-40 cap / min (1.5-2 ml / min); the maximum daily intake for adults is 500 ml.
In adults with a normal metabolism, the daily dose of dextrose administered should not exceed 4-6 g / kg, i.e. about 250 - 450 g (with a decrease in the intensity of metabolism - 30-40 ml / kg).
Children for parenteral nutrition, along with fats and amino acids, 6 g of dextrose / kg / day are administered on the first day, followed by up to 15 g / kg / day. When calculating the dose of dextrose with the administration of 5% and 10% solutions, it is necessary to take into account the permissible volume of the injected fluid: for children with a weight of 2-10 kg - 100-165 ml / kg / day, children with a weight of 10-40 kg - 45-100 ml / kg / day.
The rate of administration: at the normal state of metabolism, the maximum rate of dextrose administration to adults is 0.25-0.5 g / kg / h (with a decrease in the intensity of the metabolism, the rate of administration is reduced to 0.125-0.25 g / kg / h). In children, the rate of administration should not exceed 0.5 g / kg / h; which is 5 ml of solution - about 10 ml / min or 200 cap / min (20 cap = 1 ml).
When using a solution of glucose as a solvent, the recommended dose is 50-250 ml per dose of the drug to be dissolved, the characteristics of which are determined and the rate of administration.
For more complete assimilation of dextrose, administered in large doses, simultaneously with her, short-acting insulin is administered at the rate of 1 unit of insulin per 4-5 g of dextrose. The blood glucose content should be carefully monitored. To avoid hyperglycemia, the level of possible glucose oxidation should not be exceeded.
Patients with diabetes mellitus are administered dextrose under the control of its content in blood and urine.