Treatment should be carried out under conditions of regular and careful observation. Clinical and biological parameters, in particular plasma glucose concentration, fluid balance and plasma electrolytes,should be monitored on a regular basis and throughout the treatment period.
In the case of hyperglycemia, the rate of infusion should be carefully adjusted or the administration of short-acting insulin is prescribed. If necessary, potassium can be added.
Patients who are given high doses of dextrose solution should be monitored for development of hypervolemia, cardiac, pulmonary or severe renal failure and / or oliguria / anuria.
It is not recommended to apply the solution after acute ischemic stroke, since hyperglycemia is associated with increased ischemic damage to the brain and prevents recovery.
When carrying out any intravenous infusion, it is necessary to observe the patient's condition. Patients with diabetes mellitus are administered dextrose under the control of blood sugar and urine. In the case of administering infusion of dextrose solution, patients with kidney disease or a diabetic patient should carefully monitor glucose concentration and, if necessary, add short-acting insulin and / or potassium.
The administration of the dextrose solution should not occur simultaneously, before or after the infusion of blood with the same equipment because of the risk of hemolysis and aggregation of red blood cells.
Apply only a clear solution, with no visible mechanical impurities and if the packaging is not damaged. Enter directly after connecting to the infusion system.
Do not use a series connection of plastic containers. This can lead to air embolism due to sucking in the air left in the first container, which can occur before the solution from the next container arrives. The solution should be administered with the use of sterile equipment in compliance with the rules of aseptic and antiseptic. To avoid ingress of air into the infusion system, it should be filled with a solution.
Adding substances can be administered before infusion or during infusion through the injection site (port for drug administration).
When using additives before parenteral administration, it is necessary to check compatibility. Complete and thorough mixing in aseptic conditions is mandatory.Solutions containing additional substances should be used immediately and not stored.