The concentration and dose of the dextrose solution is determined by several factors, including age, body weight and general condition of the patients.
The blood glucose content should be carefully monitored. To avoid hyperglycemia, the level of possible glucose oxidation should not be exceeded.
Intravenously drip.
5% solution is administered at a maximum rate of up to 7 ml (150 cap / min) (400 ml / h); recommended daily doses: for adults (with a deficiency of carbohydrates and dehydration) - from 500 ml to 3 liters per day. Children: weighing up to 10 kg - 100 ml / kg per day; weighing from 10 to 20 kg - 1000 ml + 50 ml for each kilogram of weight over 10 kg per day; weighing more than 20 kg - 1500 ml + 20 ml for each kg over 20 kg per day.
Intravenously streamlined.
10-50 ml of a 5% solution. In adults with a normal metabolism, the daily dose of dextrose administered should not exceed 4-6 g / kg, i.e. about 250-450 g (with a decrease in the metabolic rate, the daily dose is reduced to 200-300 g), while the daily volume of the injected liquid is 30-40 ml / kg.
Children for parenteral nutrition on the first day, 6 g of dextrose / kg / day, followed by up to 15 g / kg / day, along with glucose, if necessary, introduce fats and amino acids. When calculating the dose of dextrose with the administration of 5% solution, you must take into account the permissible volume of the injected fluid: for children with a body weight of 2-10 kg - 100-165 ml / kg / day, children with a body weight of 10-40 kg - 45-100 ml / kg / day.
At a normal status of a metabolism maximum rate of dextrose administration adults - 0,25-0,5 g / kg / h (with a decrease in the intensity of the metabolism, the rate of administration is reduced to 0.125-0.25 g / kg / h). Children the rate of dextrose administration should not exceed 0.5 g / kg / h, which is about 10 ml / min or 200 cap / min (20 cap-1 ml).
When using a solution of glucose as a solvent, the recommended dose is 50-250 ml per dose of the drug to be dissolved, the characteristics of which are determined and the rate of administration.
Patients with diabetes mellitus are administered glucose under the control of its content in the blood and urine.