Active substanceDextroseDextrose
Similar drugsTo uncover
  • Glucose
    solution d / infusion 
  • Glucose
    solution in / in 
    GROTEKS, LLC     Russia
  • Glucose
    solution d / infusion 
  • Glucose
    solution in / in 
  • Glucose
    solution d / infusion 
    GROTEKS, LLC     Russia
  • Glucose
    solution d / infusion 
    PIELDZHI, LLC     Russia
  • Glucose
    solution d / infusion 
    ATOLL, LLC     Russia
  • Glucose
    solution in / in 
  • Glucose
    solution in / in 
    ALVILS, LTD.     Russia
  • Glucose
    solution d / infusion 
    ATOLL, LLC     Russia
  • Glucose
    solution in / in 
    ATOLL, LLC     Russia
  • Glucose
    solution d / infusion 
  • Glucose
    solution d / infusion 
    POLISAN NTPF, LLC     Russia
  • Glucose
    solution d / infusion 
  • Glucose
    solution d / infusion 
  • Glucose
    solution d / infusion 
  • Glucose
    solution in / in 
  • Glucose
    solution d / infusion 
    Baxter S.L.     Spain
  • Glucose
    solution d / infusion 
  • Glucose
    solution d / infusion 
    SAMSON-MED, LLC     Russia
  • Glucose
    solution in / in 
  • Glucose
    pills inwards 
  • Glucose
    solution d / infusion 
    ALIUM PFK, LLC     Russia
  • Glucose
    solution d / infusion 
  • Glucose
    solution d / infusion 
    GEMATEK, LLC     Russia
  • Glucose
    solution d / infusion 
  • Glucose
    solution d / infusion 
  • Glucose
    solution d / infusion 
  • Glucose
    solution in / in 
    BINNOFARM, CJSC     Russia
  • Glucose
    solution d / infusion 
  • Glucose
    solution in / in 
  • Glucose
    solution d / infusion 
    BIOSINTEZ, PAO     Russia
  • Glucose
    solution in / in 
  • Glucose
    solution d / infusion 
  • Glucose
    solution d / infusion 
  • Glucose
    solution d / infusion 
    DALHIMFARM, OJSC     Russia
  • Glucose
    solution in / in 
  • Glucose
    solution in / in 
    BIOSINTEZ, PAO     Russia
  • Glucose
    solution d / infusion 
  • Glucose
    solution in / in 
    DALHIMFARM, OJSC     Russia
  • Glucose
    solution d / infusion 
  • Glucose
    solution d / infusion 
  • Glucose
    solution d / infusion 
    SAKHAMEDPROM, SUE     Russia
  • Glucose
    solution d / infusion 
    RESTER, CJSC     Russia
  • Glucose
    solution d / infusion 
  • Glucose
    solution d / infusion 
    KRASFARMA, JSC     Russia
  • Glucose
    solution d / infusion 
    Kelun-Kazfarm, TOO     The Republic of Kazakhstan
  • Glucose Brown
    solution d / infusion 
  • Glucose bufus
    solution in / in 
    UPDATE OF PFC, CJSC     Russia
  • Glucose-Vial
    solution d / infusion 
    VIAL, LLC     Russia
  • Glucose-E
    solution d / infusion 
    ESKOM NPK, OAO     Russia
  • Glucose-Eskom
    solution in / in 
    ESKOM NPK, OAO     Russia
  • Glucose solution for infusions
    solution d / infusion 
    ALTAYVITAMINS, CJSC     Russia
  • Glucosterol
    solution d / infusion 
  • Dosage form: & nbspsolution for infusions
    Composition:

    Active substances: glucose 50 g or 100 g;

    Excipients: sodium chloride 0.26 g, solution of hydrochloric acid 0.1 M to pH 3.5-6.5, water for injection up to 1 liter.

    Description:Colorless, clear liquid.
    Pharmacotherapeutic group:Nutrition carbohydrate remedy
    ATX: & nbsp

    B.05.C   Irrigation solutions

    V.06.D   Other medications for nutrition

    V.04.C   Other diagnostic preparations

    Pharmacodynamics:

    Glucose increases oxidation-reduction processes in the body, improves the antitoxic function of the liver, covers part of the energy expenditure of the body. The infusion of dextrose solutions quickly replenishes the water deficiency. Glucose entering the tissues is phosphorylated, turning into glucose-6-phosphate, which is actively included in many parts of the body's metabolism.

    Isotonic 5% glucose solution has a detoxification, metabolic action, restores the volume of circulating blood, is a source of valuable easily digestible nutrient. With the metabolism of glucose in tissues, a significant amount of energy necessary for the life of the organism is released.

    Hypertensive (10%) glucose solution increases osmotic blood pressure, improves metabolism; increases myocardial contractility; improves the antitoxic function of the liver, dilates blood vessels, increases diuresis.

    Theoretical osmolarity of 10% dextrose is 555 mOsm / l.

    Pharmacokinetics:

    It is absorbed completely by the body, the kidneys are not excreted (the appearance in the urine is a pathological sign).

    Indications:

    Hypoglycemia, insufficiency of carbohydrate nutrition, toxicoinfection, intoxications in liver diseases (hepatitis, dystrophy and atrophy of the liver, including hepatic insufficiency), hemorrhagic diathesis; dehydration (vomiting, diarrhea, postoperative period); collapse, shock.

    Isotonic solution of dextrose (5%) used to fill the volume of fluid in the cell and general dehydration, extracellular hyperhydration.

    Hypertonic solution of dextrose (10%) Used for hypoglycemia and liver diseases; severe infectious diseases; various intoxications; hemorrhagic diathesis, for parenteral nutrition.

    Dextrose solutions can be used both independently and for dilution of drugs for intravenous administration.

    Contraindications:

    Hyperglycemia, hypersensitivity, hyperlactacidemia, hyperhydration, postoperative disorders of glucose utilization; edema of the brain, pulmonary edema, acute left ventricular failure, hyperosmolar coma.

    Carefully:

    Decompensated chronic heart failure, diabetes mellitus, chronic renal failure (oligo-, anuria), hyponatremia.

    Dosing and Administration:

    Isotonic dextrose solution (5%) injected subcutaneously to 300-500 ml, intravenously (drip) with a maximum rate of up to 150 cap / min, the maximum daily dose of 2000 ml, rectally in enemas 300-500 ml of solution per day;

    hypertensive solution (10%) - intravenously - up to 60 cap / min; the maximum daily dose for adults is 1000 ml.

    Intravenously sprayed - 10-50 ml of 5% and 10% solutions.

    In adults with a normal metabolism, the daily dose of dextrose administered should not exceed 4-6 g / kg / day, i.e. about 250-450 g / day (with a decrease in the metabolic rate, the daily dose is reduced to 200-300 g), while the volume of the injected liquid is 30-40 ml / kg / day.

    Children for parenteral nutrition, along with fats and amino acids, 6 g of dextrose / kg / day are administered on the first day, followed by up to 15 g / kg / day. When calculating the dose of dextrose with the administration of 5% and 10% solutions, it is necessary to take into account the permissible volume of the injected fluid: for children with a weight of 2-10 kg - 100-165 ml / kg / day, children with a weight of 10-40 kg - 45-100 ml / kg / day.

    Rate of administration: at the normal state of metabolism, the maximum rate of administration to adults is 0.25-0.5 g / kg / h (with a decrease in the intensity of the metabolism, the rate of administration is reduced to 0.125-0.25 g / kg / h). In children, the rate of administration should not exceed 0.5 g / kg / h; which is 5% solution - about 10 ml / min - 200 drops / minute (20 drops = 1 ml).

    In cases of severe dehydration, 3-5 liters of isotonic solution of dextrose are possible.

    Diabetic patients with dextrose are administered under the control of its content in the blood and urine.

    Side effects:

    Hyperglycemia, fever, hypervolemia, acute left ventricular failure.

    At the injection site - the development of infection, thrombophlebitis.

    Overdose:

    Symptoms: hyperglycemia, glucosuria, hyperglycemic hyperosmolar coma, hyperhydration, disturbance of water-electrolyte balance.

    Treatment: to stop the introduction of glucose, to introduce insulin, symptomatic therapy.
    Interaction:

    When combined with other drugs, it is necessary to visually check compatibility.

    Special instructions:

    For more complete assimilation of glucose, administered in large doses, concomitantly with her, insulin is administered subcutaneously at the rate of 1 unit of insulin per 4-5 g of glucose.

    When glucose solutions are introduced, control of electrolyte balance, glucose in the blood and urine is necessary.

    To increase osmolarity, 5% glucose solution can be combined with 0.9% sodium chloride solution.

    Form release / dosage:

    Solution for infusions, 5% and 10%.

    Packaging:

    By 100, 200, 250, 400 and 500 ml into polymeric containers of multilayer film based on polypropylene.

    Containers of 80 pieces with a capacity of 100 ml, containers of 20 pieces with a capacity of 400 and 500 ml and containers of 40 pieces with a capacity of 200 and 250 ml are placed in boxes of cardboard corrugated.

    In the container box, 80, 20 and 40 instructions for use, respectively.

    Polymer containers of multilayer film, with a capacity of 100, 200 and 250 ml in individual packaging with instructions for use.

    Storage conditions:

    Store in a dry place, protected from light, out of reach of children, at a temperature not exceeding 25 ° C.

    Freezing the drug (provided that the packaging is kept sealed) is not a contraindication to its use.

    Shelf life:

    2 years.

    Do not use after the expiry date printed on the package.

    Terms of leave from pharmacies:On prescription
    Registration number:LSR-001520/08
    Date of registration:14.03.2008
    Expiration Date:Unlimited
    The owner of the registration certificate:SAKHAMEDPROM, SUE SAKHAMEDPROM, SUE Russia
    Manufacturer: & nbsp
    Information update date: & nbsp21.04.2017
    Illustrated instructions
      Instructions
      Up