Glucose - instructions for use, dose, side effects, contraindications

Active substance:
Dextrose monohydrate (in terms of anhydrous substance)	400 mg
Excipients:
Sodium chloride	0.26 mg
A 0.1 M solution of hydrochloric acid	to pH 3.0-4.0
Water for injections	up to 1.0 ml

Description:Transparent, colorless or slightly yellowish liquid.

Pharmacotherapeutic group:Nutrition carbohydrate remedy

ATX: & nbsp

B.05.C Irrigation solutions

V.06.D Other medications for nutrition

V.04.C Other diagnostic preparations

Pharmacodynamics:

Participates in various metabolic processes in the body. The infusion of dextrose solutions partially replenishes the water deficiency. Dextrose, entering the tissue, phosphorylated, turning into glucose-6-phosphate, which is actively included in many parts of the body's metabolism.

Increases osmotic pressure of blood, increases diuresis.

Pharmacokinetics:

Dextrose is fully absorbed by the body, the kidneys are not excreted (appearance in the urine is a pathological sign).

Indications:

Hypoglycemia, insufficiency of carbohydrate nutrition.

Contraindications:

Hypersensitivity, hyperglycemia, hyperlactacidemia, hyperhydration, postoperative disorders of glucose utilization; circulatory disorders that threaten edema of the brain and lungs; cerebral edema, pulmonary edema, acute left ventricular failure, hyperosmolar coma, children's age (without breeding).

Carefully:

Decompensated chronic heart failure, chronic renal failure (oligo, anuria), hyponatremia, diabetes mellitus.

Pregnancy and lactation:

It is possible to use dextrose during pregnancy and during breastfeeding according to the indications and under the strict supervision of a doctor.

Dosing and Administration:

Intravenously drip - up to 30 drops / minute (1.5 ml / min) to 50 ml per injection; if necessary - intravenously drip in the composition of blood substituting and anti-shock liquids.

The maximum daily dose for adults 250 ml.

For more complete assimilation of dextrose, administered in large doses, concurrently with it, insulin is administered with a short action, at the rate of 1 unit of short-acting insulin for 4-5 g of dextrose.

After breeding, you can apply in children (in a concentration of no more than 20-25%). Children for parenteral nutrition along with fats and amino acids on the first day, 6 grams of dextrose / kg / day, followed by up to 15 g / kg / day. The rate of administration should not exceed 0.75 g / kg / h.

Side effects:

In the place of administration, infection, thrombophlebitis may develop.

Overdose:

Symptoms: hyperglycemia, glucosuria, hyperglycaemic,hyperosmolar coma, hyperhydration, disturbance of water-electrolyte balance, fatty liver infiltration, acute left ventricular failure, ion balance disturbance.

Treatment: stop the introduction of dextrose, introduce short-acting insulin, symptomatic therapy.

Interaction:

When combined with other medicines, it is necessary to control the pharmaceutical compatibility, incl. visually.

Special instructions:

Dextrose solution can not be administered quickly or for a long time.

If a chill occurs during the administration of the solution, the administration should be stopped immediately.

To prevent thrombophlebitis, should be administered slowly, through large veins.

Patients with diabetes mellitus are administered dextrose under the control of its content in blood and urine.

It can be used as a component of various blood substitute and anti-shock liquids and for the preparation of solutions of drugs for intravenous administration.

Effect on the ability to drive transp. cf. and fur:

The use of the drug does not affect the management of vehicles.

Form release / dosage:

Solution for intravenous administration, 400 mg / ml.

Packaging:

5 ml or 10 ml in ampoules of colorless neutral glass type I with a colored break ring or with a colored dot and a notch or without a kink ring, a colored dot and a notch. One, two or three color rings and / or a two-dimensional bar code, and / or alphanumeric coding or without additional color rings, a two-dimensional bar code, and alphanumeric coding can additionally be applied to the ampoules.

5 ampoules per contour cell pack of film polyvinylchloride and aluminum foil lacquer or film polymer or without foil and without film.

Or 5 ampoules in a prefabricated form (tray) made of cardboard with cells for laying ampoules.

1 or 2 contour squares or cardboard tracks together with the instruction for use and a scarifier or knife with an ampoule or without a scarifier and a knife ampoule in a cardboard package (bundle).

Storage conditions:

In the dark place at a temperature of no higher than 25 ° C. Do not freeze.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after the expiration date.

Terms of leave from pharmacies:On prescription

Registration number:LP-002184

Date of registration:19.08.2013 / 07.08.2015

Expiration Date:19.08.2018

Date of cancellation:2018-08-19

The owner of the registration certificate:ATOLL, LLC ATOLL, LLC Russia

Manufacturer: & nbsp

OZONE, LLC Russia

Representation: & nbspOZONE LLC OZONE LLC Russia

Information update date: & nbsp03.05.2017

Illustrated instructions

Instructions

Glucose (Glucose)