Active substanceDextroseDextrose
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  • Dosage form: & nbsp
    solution for intravenous administration
    Composition:Per 1 ml:

    Active substance:

    Dextrose Monohydrate

    440.0 mg

    in terms of dextrose anhydrous

    400.0 mg

    Excipients:

    Sodium chloride

    0.26 mg

    Hydrochloric acid

    q.s.

    Water for injections

    up to 1.0 ml

    Description:Transparent, colorless or light yellow liquid.
    Pharmacotherapeutic group:Nutrition carbohydrate remedy
    ATX: & nbsp

    B.05.C   Irrigation solutions

    V.06.D   Other medications for nutrition

    V.04.C   Other diagnostic preparations

    Pharmacodynamics:

    Participates in various metabolic processes in the body. The infusion of dextrose solutions partially replenishes the water deficiency. Dextrose, entering the tissue, phosphorylated, turning into glucose-6-phosphate, which is actively included in many parts of the body's metabolism.

    Increases osmotic pressure of blood, increases diuresis.

    Pharmacokinetics:Dextrose is fully absorbed by the body, the kidneys are not excreted (appearance in the urine is a pathological sign).
    Indications:

    Hypoglycemia, insufficiency of carbohydrate nutrition.

    Contraindications:

    Hypersensitivity, hyperglycemia, hyperlactacidemia, hyperhydration, postoperative disorders of glucose utilization; circulatory disorders that threaten edema of the brain and lungs; cerebral edema, pulmonary edema, acute left ventricular failure, hyperosmolar coma, children's age (without breeding).

    Carefully:

    Decompensated chronic heart failure, chronic renal failure (oligo, anuria), hyponatremia, diabetes mellitus.

    Pregnancy and lactation:

    It is possible to use dextrose during pregnancy and during breastfeeding according to the indications and under the strict supervision of a doctor.

    Dosing and Administration:

    Intravenously drip - up to 30 drops / minute (1.5 ml / min) to 50 ml per injection; if necessary - intravenously drip in the composition of blood substituting and anti-shock liquids.

    The maximum daily intake for adults is 250 ml.

    For more complete assimilation of dextrose, administered in large doses, concurrently with it, insulin is administered with a short action, at the rate of 1 unit of short-acting insulin for 4-5 g of dextrose.

    After breeding, you can apply in children (in a concentration of no more than 20-25%). Children for parenteral nutrition along with fats and amino acids on the first day, 6 grams of dextrose / kg / day, followed by up to 15 g / kg / day. The rate of administration should not exceed 0.75 g / kg / h.

    Side effects:In the place of administration, infection, thrombophlebitis may develop.
    Overdose:

    Symptoms: hyperglycemia, glucosuria, hyperglycaemic, hyperosmolar coma,hyperhydration, violation of water-electrolyte balance, fatty liver infiltration, acute left ventricular failure, ion balance disturbance.

    Treatment: stop the introduction of dextrose, introduce short-acting insulin, symptomatic therapy.

    Interaction:

    When combined with other medicines, it is necessary to control the pharmaceutical compatibility, incl. visually.

    Special instructions:

    Dextrose solution can not be administered quickly or for a long time. If a chill occurs during the administration of the solution, the administration should be stopped immediately.

    To prevent thrombophlebitis should be administered slowly, through large veins.

    Patients with diabetes mellitus are administered dextrose under the control of its content in blood and urine.

    It can be used as a component of various blood substitute and anti-shock liquids and for the preparation of solutions of drugs for intravenous administration.

    Effect on the ability to drive transp. cf. and fur:

    The drug does not affect the ability to drive vehicles and engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

    Form release / dosage:

    Solution for intravenous administration, 400 mg / ml.

    Packaging:For 10 ml in ampoules of colorless transparent glass with a break point. For each ampoule a label is applied or labeled with a quick-fixing paint.
    10 ampoules per blister of PVC, 1 blister each, along with instructions for medical use in a pack of cardboard.
    Storage conditions:

    Store at a temperature not exceeding 30 ° C. Freezing the drug, provided that the ampoules remain sealed, is not a contraindication to its use.

    Keep out of the reach of children.

    Shelf life:

    5 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:LP-002293
    Date of registration:05.11.2013 / 29.08.2014
    Expiration Date:05.11.2018
    Date of cancellation:2018-11-05
    The owner of the registration certificate:ALVILS, LTD. ALVILS, LTD. Russia
    Manufacturer: & nbsp
    Representation: & nbspAlvils, OOOAlvils, OOO
    Information update date: & nbsp03.05.2017
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