Dextrose solution 5%: intravenously (drip). The concentration and dose of the administered solution depend on the age, body weight and clinical state of the patient. The blood glucose content should be carefully monitored.
Recommended adult dose (body weight about 70 kg): from 500 to 3000 ml per day.
Recommended dose for children:
- body weight up to 10 kg - 100 ml / kg per day;
- body weight from 10 to 20 kg - 1000 ml + 50 ml for each kg more than 10 kg per day;
- body weight above 20 kg - 1500 ml + 20 ml for each kg over 20 kg per day.
The rate of infusion depends on the clinical condition of the patient.
Do not exceed the threshold of glucose utilization in the body in order to avoid hyperglycemia.
The maximum dose of dextrose for adults:
From 5 mg / kg / min to 10-18 mg / kg / min; for children, depending on age and total body weight.
The recommended dose for use for dilution and dissolution, parenterally administered drugs (as the base solution) is from 50 to 250 ml per dose of the drug administered. In this case, the dose and rate of administration of the solution are determined by the characteristics of the drug dissolved in it.
Dextrose solution 10%: intravenously (drip). The concentration and dose of the administered solution depend on the age, body weight and clinical state of the patient. The blood glucose content should be carefully monitored.
The recommended dose for adults and the elderly (body weight about 70 kg):
- as sources of carbohydrates, for the prevention and treatment of moderate hypoglycemia, with isotonic extracellular dehydration - from 500 to 3000 ml per day (7 to 40 ml / kg / day). To avoid exceeding the glucose disposal threshold in the body, the maximum dose should not exceed 5 mg / kg / min (3 ml / kg / h).
Duration of treatment depends on the clinical condition of the patient.
- for dilution and dissolution of parenterally administered drugs (as a base solution) from 50 to 250 ml per dose of the drug administered.The dose, the rate of administration of the solution, and the duration of treatment depend on the solute.
Recommended doses for children and adolescents:
- as sources of carbohydrates, for the prevention and treatment of moderate hypoglycemia, with isotonic extracellular dehydration:
- with a body weight of up to 10 kg - 100 ml / kg per day;
- with a body weight of 10 to 20 kg - 1000 ml + 50 ml per kg over 10 kg per day;
- with a body weight above 20 kg - 1500 ml + 20 ml for each kg over 20 kg per day.
To avoid exceeding the glucose utilization threshold in the body maximum daily dose should be:
- for premature and full-term newborns - from 6 to 11 ml / kg / h;
- for children from 1 to 3 years - from 5 to 8 ml / kg / h;
- for children from 4 to 6 years - from 5 to 7 ml / kg / h;
- for children from 7 to 10 years - from 4 to 7 ml / kg / h;
- for children over 11 years old - 4 ml / kg / h.
Duration of treatment it depends on the clinical condition of the patient.
For more complete assimilation of dextrose, administered in large doses, concurrently with it, insulin is administered with a short action, at the rate of 1 unit of short-acting insulin for 4-5 g of dextrose.
Depending on the clinical state of the patient, the rate of administration may be reduced to reduce the risk of osmotic diuresis.
Do not re-connecting partially used bottle polypropylene (regardless of the number remaining therein solution).
Dispose of the containers after a single use.
Dispose of each unused dose.