Active substanceDextroseDextrose
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  • Dosage form: & nbspsolution for intravenous administration
    Composition:

    Active substance: dextrose monohydrate (in terms of dry matter) 400.0 mg;

    Excipients: sodium chloride 0.26 mg, hydrochloric acid solution 1 M to pH 3.0-4.0, water for injection up to 1 ml.

    Description:

    Transparent, colorless or slightly colored liquid.

    Pharmacotherapeutic group:Nutrition carbohydrate remedy
    ATX: & nbsp

    B.05.C   Irrigation solutions

    V.06.D   Other medications for nutrition

    V.04.C   Other diagnostic preparations

    Pharmacodynamics:
    Participates in various metabolic processes in the body. The infusion of dextrose solutions partially replenishes the water deficiency. Dextrose, entering the tissue, phosphorylated, turning into glucose-6-phosphate, which is actively included in many parts of the body's metabolism. Increases osmotic pressure of blood, increase diuresis.
    Pharmacokinetics:

    Dextrose is fully absorbed by the body, the kidneys are not excreted (appearance in the urine is a pathological sign).

    Indications:

    - Hypoglycemia;

    - insufficiency of carbohydrate nutrition.

    As a component of various blood-substituting and anti-shock fluids; for the preparation of solutions of drugs for intravenous administration.

    Contraindications:

    - Hypersensitivity;

    - hyperglycemia;

    - hyperlactacidemia;

    - hyperhydration;

    - postoperative disorders of glucose utilization;

    - circulatory disorders that threaten edema of the brain and lungs;

    - cerebral edema;

    - pulmonary edema;

    - acute left ventricular failure;

    - hyperosmolar coma,

    - childhood.

    Carefully:Diabetes mellitus, decompensated chronic heart failure, chronic renal failure (oligo-, anuria), hyponatremia.
    Pregnancy and lactation:

    It is possible to use dextrose during pregnancy and during breastfeeding according to the indications and under the strict supervision of a doctor.

    Dosing and Administration:

    Intravenously with a maximum speed of up to 30 cap / min (1.5 ml / min) to 50 ml per injection, if necessary - intravenously drip in the composition of blood substituting and anti-shock liquids. The maximum daily intake for adults is 250 ml.

    Patients with diabetes mellitus are administered glucose under the control of its content in the blood and urine.

    Side effects:

    In the place of administration, infection may develop, thrombophlebitis.

    Overdose:

    Symptoms: hyperglycemia, glucosuria, hyperglycemic hyperosmolar coma, hyperhydration, disturbance of water-electrolyte balance, fatty liver infiltration, hyperglycemia, acute left ventricular failure, ion balance disturbance.

    Treatment: stop the introduction of glucose, introduce short-acting insulin, symptomatic therapy.

    Interaction:

    When combined with other medicines, it is necessary to control the pharmaceutical compatibility, incl. visually.

    Special instructions:

    Glucose solution can not be administered quickly or for a long time. If a chill occurs during the administration of the solution, the administration should be stopped immediately.

    To prevent thrombophlebitis should be administered slowly, through large veins.

    Effect on the ability to drive transp. cf. and fur:

    The use of the drug does not affect the management of vehicles.

    Form release / dosage:

    Solution for intravenous administration, 400 mg / ml.

    Packaging:

    5 ml or 10 ml into neutral glass ampoules.

    For 10 ampoules with instruction for use and a knife for opening ampoules or a scarifier ampullum is placed in a box of cardboard.

    5 or 10 ampoules are placed in a contoured cell pack of a polyvinylchloride film or polyethylene terephthalate tape and aluminum foil or paper with a polyethylene coating or without a foil, or without paper.

    For 1 or 2 contour packs with instructions for use and a knife for opening ampoules or a scarifier ampullum is placed in a pack of cardboard.

    When you pack the ampoules with a break ring or break point, the ampoule opener or ampoule scapper is not put in.

    Storage conditions:

    Store at a temperature of 5 to 30 ° C.

    Keep out of the reach of children.

    Shelf life:

    6 years.

    Do not use after the expiry date printed on the package.

    Terms of leave from pharmacies:On prescription
    Registration number:P N000855 / 01
    Date of registration:13.06.2011
    Expiration Date:Unlimited
    The owner of the registration certificate:NOVOSIBHIMFARM, OJSC NOVOSIBHIMFARM, OJSC Russia
    Manufacturer: & nbsp
    Representation: & nbspNOVOSIBHIMFARM, OJSCNOVOSIBHIMFARM, OJSC
    Information update date: & nbsp21.04.2017
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