Glucose - instructions for use, dose, side effects, contraindications

Glucose increases oxidation-reduction processes in the body, improves the antitoxic function of the liver, covers part of the energy expenditure of the body, as it is a source of easily assimilated carbohydrates. Entering the tissue is phosphorylated, turning into glucose-6-phosphate, which is actively included in many parts of the body's metabolism.

40% solution is hypertonic. When the hypertonic solution is injected into the vein, the osmotic blood pressure rises, the contractile activity of the cardiac muscle increases, the vessels expand, the detoxification function of the liver improves, and the diuresis increases.

Pharmacokinetics:

It is absorbed completely by the body, the kidneys are not excreted (the appearance in the urine is a pathological sign).

Indications:

Hypoglycemia, insufficiency of carbohydrate nutrition, toxicinfection, intoxications in liver diseases (hepatitis, dystrophy and atrophy of the liver, including liver failure), hemorrhagic diathesis; intoxication acid and its salts, carbon monoxide, aniline, arsenic hydrogen, phosgene, etc.); collapse, shock.

As a component of various blood-substituting and anti-shock fluids; for the preparation of solutions of drugs for intravenous administration.

Contraindications:

Hypersensitivity, hyperglycemia, hyperlactacidemia, hyperhydration, postoperative disorders of glucose utilization; circulatory disorders that threaten edema of the brain and lungs; edema of the brain, pulmonary edema, acute left ventricular failure, hyperosmolar coma.

Carefully:

Decompensated chronic heart failure, chronic renal failure (oligo, anuria), hyponatremia, diabetes mellitus.

Dosing and Administration:

Intravenously, struyno 10-50 ml once, if necessary - intravenously drip - up to 30 cap / min (1.5 ml / min). The maximum daily intake for adults is 250 ml.

For more complete assimilation of glucose, administered in large doses, simultaneously with her, insulin is prescribed at the rate of 1 unit of insulin per 4-5 g of glucose.

Diabetes patients with glucose are administered under the control of its content in the blood and urine.

Side effects:

Ion balance disorders, hyperglycemia, glucosuria, fever, hypervolemia, acute left ventricular failure.

At the injection site - the development of infection, thrombophlebitis.

Overdose:

Symptoms: hyperglycemia, glucosuria, hyperglycemic hyperosmolar coma, hyperhydration, disturbance of water-electrolyte balance.

Treatment: to stop the introduction of glucose, to introduce insulin, symptomatic therapy.

Interaction:

Glucose solution should not be mixed with alkaloids (their decomposition occurs), with general anesthetics (decreased activity); glucose weakens the action of analgesic, adrenomimetic drugs, inactivates streptomycin, reduces the effectiveness of nystatin.

Special instructions:

Glucose solution can not be administered quickly or for a long time.

If a chill occurs during the injection of the solution, the administration should be stopped immediately.

To prevent thrombophlebitis, the solution should be administered slowly, through large veins.

When combined with other drugs, it is necessary to visually check compatibility.

Form release / dosage:

Solution for intravenous administration, 400 mg / ml.

Packaging:

5 ml, 10 ml in ampoules.

10 ampoules of 10 ml each are placed in carton boxes for consumer packaging with a paper insert.

5 ampoules of 5 ml or 10 ml are placed in a contiguous cell pack of a polyvinyl chloride film.

For 1, 2 contour mesh packages are placed in a pack of cardboard.

In each pack, the box is enclosed with the instruction for use, the ampoule knife or the scarifier (when packing ampoules with a break ring, a point and an incision, an ampoule knife or a scarifier do not invest).

Storage conditions:

At a temperature of 5 to 30 ° C.

Note. Freezing the drug, provided that the ampoules remain sealed, is not a contraindication to its use.

Keep out of the reach of children.

Shelf life:

5 years.

Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:On prescription

Registration number:P N001631 / 01

Date of registration:10.09.2008

Expiration Date:Unlimited

The owner of the registration certificate:BIOSINTEZ, PAO BIOSINTEZ, PAO Russia

Manufacturer: & nbsp

BIOSINTEZ, PAO Russia

Representation: & nbspBIOSINTEZ JSC BIOSINTEZ JSC Russia

Information update date: & nbsp21.04.2017

Illustrated instructions

Instructions

Glucose (Glucose)