Often - 1-10%; not often - 0.1-1%, rarely - 0.01-0.1%, very rarely - less than 0.001%, including individual cases.
It should be remembered that the intensity of side effects depends on the dose and varies in different patients. Risk of injury. The gastrointestinal tract (GIT) directly depends on the dose and duration of administration. The most common side effects are lesions GIT.
From the digestive system: often - nausea, vomiting and diarrhea, dyspepsia, flatulence, anorexia, abdominal pain, increased activity of aminotransferases; rarely - gastrointestinal ulcers (with or without bleeding or perforation), gastritis, gastrointestinal bleeding, bloody vomiting,melena or bloody diarrhea, hepatitis, jaundice; very rarely - colitis (including colitis with blood, exacerbation of ulcerative colitis or Crohn's disease), constipation, stomatitis, glossitis, esophageal lesions, narrowing of the intestinal lumen, pancreatitis, fulminant hepatitis. "
From the nervous system: often - headache, dizziness, weakness; rarely - drowsiness; very rarely - disorders of sensitivity (including paresthesia), memory disorders, convulsions, anxiety, tremor, aseptic meningitis, nightmares, depression, disorientation.
From the sense organs: often - vertigo; very rarely - visual impairment (blurred vision, diplopia), hearing impairment, tinnitus, a violation of taste sensations.
From the urinary system: very rarely - acute renal failure, hematuria, proteinuria, interstitial nephritis, nephrotic syndrome, papillary necrosis.
Co sides of hemopoiesis: very rarely - hematopoietic disorders (hemolytic and aplastic anemia, leukopenia, agranulocytosis, thrombocytopenia).
Allergic reactions: rarely anaphylactic / anaphylactoid reactions, including a marked decrease in blood pressure (BP) and shock; very rarely - angioedema (including face).
From the cardiovascular system: very rarely - palpitation, chest pain, heart failure, increased blood pressure, vasculitis, myocardial infarction.
From the respiratory system: rarely - bronchial asthma (including dyspnea); very rarely - pneumonia.
From the skin: often - a rash; rarely - hives; very rarely - bullous eruptions, erythema, including multiform and Stevens-Johnson syndrome, Lyell's syndrome, exfoliative dermatitis, itching, hair loss, photosensitivity, purpura, including allergic.
Other: rarely - swelling.