Diclofenac grindex - instructions for use, dose, side effects, contraindications

auxiliary substances: benzyl benzoate - 60 mg, carbomer - 15 mg, polysorbate 80 -10 mg, sodium hydroxide - 5.6 mg, imidazolidinyl urea - 5 mg, purified water - up to 1 g.

Description:

Ointment is white or almost white.

Pharmacotherapeutic group:Non-steroidal anti-inflammatory drug (NSAID).

ATX: & nbsp

S.01.B.C.03 Diclofenac

M.01.A.B.05 Diclofenac

Pharmacodynamics:Active substance of ointment - diclofenac - Non-steroidal anti-inflammatory drug (NSAID), which has pronounced analgesic and anti-inflammatory properties. Indiscriminately inhibiting cyclooxygenase type 1 and 2, disrupts the metabolism of arachidonic acid and the synthesis of prostaglandins, which are the main link in the development of inflammation.

Diclofenac is used to eliminate the pain syndrome and reduce the swelling associated with the inflammatory process. When applied externally, the pain in the joints relaxes or disappears at rest and during movement.Reduces the morning stiffness and swelling of the joints, contributes to an increase in the volume of movements.

Pharmacokinetics:At application system absorption is not more than 6%. The connection with plasma proteins is 99.7%. It is excreted by the kidneys. When applied to the area of the affected joint, the concentration in the synovial fluid is higher than in the plasma.

Indications:

The drug is intended for symptomatic therapy, reducing pain and inflammation at the time of application, the progression of the disease is not affected.

- Post-traumatic inflammation of soft tissues and joints, for example, as a result of stretching, overstrain and bruises.

- Rheumatic diseases of soft tissues (tendovaginitis, bursitis, lesion of periarticular tissues).

- Pain and swelling associated with diseases of the muscles and joints (rheumatoid arthritis, osteoarthritis, radiculitis, lumbago, sciatica, muscular pain of rheumatic and rheumatic origin).

Contraindications:Hypersensitivity to diclofenac or other components of the drug, acetylsalicylic acid or other NSAIDs; complete or incomplete combination of bronchial asthma, recurrent nasal polyposis and paranasal sinuses and intolerance to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs (incl.in the anamnesis); pregnancy (III trimester), lactation period, children's age (up to 6 years), violation of the integrity of the skin at the site of the intended application.

Carefully:Hepatic porphyria (exacerbation), erosive and ulcerative lesions of the gastrointestinal tract, severe violations of the liver and kidney function, chronic heart failure, elderly age, bronchial asthma, blood clotting disorders (including hemophilia, lengthening bleeding time, tendency to bleeding ), pregnancy (I and II trimester).

Pregnancy and lactation:

Application in the I and II trimesters of pregnancy is possible only after consulting a doctor. The drug should not be used in the III trimester of pregnancy.

Experience in using the drug during lactation is not available, so the use is not recommended.

Dosing and Administration:

Outwardly.

Adults and children over 12 years of age the drug is applied a thin layer on the painful area 3-4 times a day and lightly rubbed. The required amount of the drug depends on the size of the painful area. A single dose of the drug is 2-4 grams of ointment (which in terms of volume is comparable to the size of the hazelnut). The maximum allowed daily dose is 8 g of ointment.

Children from 6 to 12 years old apply not more than 2 times a day, a single dose of the drug to 2 g. "After applying the drug, the hands should be washed.

The duration of treatment depends on the indications and the effect observed. After 2 weeks of use, consult a physician.

If you forgot to apply the drug

If you forget to use the drug, do it as quickly as possible and continue to use as usual. Do not use a double dose if the previous time of the drug was missed.

PRECAUTIONS FOR USE

Ointment should be applied only to intact skin, avoiding getting on open wounds. After applying, it is not necessary to apply an octoposion bandage. Do not allow the drug to reach the mucous membranes and eyes.

When using the drug together with other dosage forms of diclofenac, the maximum daily dose should be taken into account.

When applied to large areas of the skin for a long time, the risk of systemic side effects, characteristic of NSAIDs, increases.

Side effects:

Local reactions: eczema, photosensitivity, contact dermatitis (itching, redness, swelling of the treated skin, papules, vesicles, peeling).

Systemic reactions: generalized skin rash, allergic reactions (urticaria, angioedema, bronchospastic reactions).

Prolonged application of the ointment and / or application of ointments large quantities of systemic side effects may occur, typical of NSAIDs (see. "Overdose" section).

If side effects occur (also not listed side effects), inform the doctor.

Overdose:

Very low systemic absorption of the active ingredient of the drug when applied externally makes practically impossible overdose.

When used incorrectly or accidentally swallowed ointments may be systemic side effects - disorders of the gastrointestinal (epigastric pain, nausea, bloating and loss of appetite), and / or disorders of the nervous system (headache, dizziness, drowsiness). When symptoms of overdose or when. If you suspect an overdose, consult a doctor. Take the medicine package with you to the doctor.

Interaction:The drug may enhance the effect of drugs that cause photosensitivity. Clinically significant interaction with other drugs has not been described.

Special instructions:Drugs should not be disposed of in sewers or together with household waste. Consult a pharmacist about how to destroy medicines that are no longer used. These measures help to protect the environment.

Effect on the ability to drive transp. cf. and fur:The drug does not affect the ability to drive vehicles and work with technical devices.

Form release / dosage:

Ointment for external use 20 mg / g.

Packaging:30 g or 50 g in an aluminum tube with an internal surface lacquered, with a protective aluminum membrane on the neck and a cone-shaped device for puncturing the membrane in a screwed-in Bushon made of plastic. The tube together with the instruction for use is placed in a pack of cardboard box.

Storage conditions:Store at a temperature not exceeding 25 ° C. Do not store in the refrigerator and freezer. Keep out of the reach of children.

Shelf life:

2 years.

Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:П N011914 / 01

Date of registration:03.06.2011/ 08.02.2013

Expiration Date:indefinite

The owner of the registration certificate:GRINDEX, JSC GRINDEX, JSC Latvia

Manufacturer: & nbsp

TALLINNA FARMAATSIATEHASE, A.S. Estonia

Representation: & nbspGrindeks Rus, Open CompanyGrindeks Rus, Open CompanyRussia

Information update date: & nbsp25.12.2016

Illustrated instructions

Instructions

Diclofenac Grindeks (Diclofenac grindeks)