Diclofenaclong - instructions for use, dose, side effects, contraindications

Excipients: hypromellose 0.005 g, sorbic acid 0.001 g, sodium hydrophosphate dodecahydrate 0.0119 g, potassium dihydrogen phosphate 0.0045 g, sodium chloride 0.0041 g, water purified to 1 ml.

Description:A clear, colorless solution or a clear solution of a yellowish color.

Pharmacotherapeutic group:Non-steroidal anti-inflammatory drug (NSAID).

ATX: & nbsp

S.01.B.C.03 Diclofenac

M.01.A.B.05 Diclofenac

Pharmacodynamics:

Diclofenac - a derivative of phenylacetic acid, has an anti-inflammatory and analgesic effect. The mechanism of action is due to indiscriminate inhibition of cyclooxygenase 1 and 2, which leads to suppression of the synthesis of prostaglandins in the inflammatory focus.

When using a 0.1% solution of eye drops diclofenac reduces inflammation of the eye, resulting from infection, trauma or surgery; reduces miosis during surgical operations, reduces the synthesis of prostaglandins in the moisture of the anterior chamber.

Pharmacokinetics:The maximum concentration of the substance in the cornea and in the conjunctiva is reached by 30 minutes after instillation. The drug penetrates into the anterior chamber of the eye; in the systemic circulation in therapeutically significant concentrations is not received.

Indications:

- inhibition of miosis during surgery for cataracts;

- treatment and prevention of inflammatory processes after surgical interventions on the eyeball;

- prevention of cystic edema of the macula after operations for cataracts;

- treatment of non-infectious conjunctivitis;

- treatment and prevention of post-traumatic inflammatory process with penetrating and non-penetrating injuries of the eyeball (as an addition to local antibiotic therapy).

Contraindications:

- hypersensitivity to the components of the drug;

- violation of hematopoiesis of unknown origin;

- erosive and ulcerative processes in the gastrointestinal tract in the acute stage.

Carefully:- epithelial herpetic keratitis (including in the anamnesis); diseases that cause a clotting disorder (including hemophilia, prolonged bleeding time, a tendency to bleed); bronchial asthma caused by the intake of acetylsalicylic acid; elderly age.Children under 18 years of age should be used only if the expected curative effect exceeds the risk of possible side effects.

Pregnancy and lactation:

There are no data on the use of the drug during pregnancy, during lactation. Therefore, the use of the drug in these categories of patients should only be if the intended benefit to the mother exceeds the possible risk of side effects

effects on the fetus or the baby.

Dosing and Administration:

Locally. To inhibit intraoperative miosis, the drug is instilled in the conjunctival sac for 2 hours at intervals of 30 minutes (4 times) before surgery.

To prevent cystic edema of the macula, the drug is instilled 1 drop 3 times a day for 2-3 weeks after the operation.

With a therapeutic purpose, assign 1 drop 3-4 times a day, depending on the severity of the condition. The course of treatment can last from 1 to 2 weeks.

Side effects:

In rare cases, during the application of the drug, the following undesirable side effects are noted: mild or moderate burning, temporary loss of vision clearness immediately after instillation of eye drops, corneal opacity (throat), iritis.

Allergic reactions: itching in the eyes, hyperemia, angioedema, fever, chills, nausea, vomiting, photosensitivity, local skin allergic reactions in the form of itching and redness.

Overdose:Data on drug overdose are absent.

Interaction:If necessary, can be used simultaneously with other eye drops, including those containing glucocorticosteroids. In this case, the interval between instillations should be at least 5 minutes to prevent the leaching of active substances by subsequent doses.

Special instructions:

During the treatment with the drug, it is not recommended to wear soft contact lenses. When using hard lenses, you should remove them before applying the drug and re-dress 15-20 minutes after instillation.

If there is an infection or a threat of its development, local antibacterial treatment is prescribed at the same time.

During the period of treatment, care must be taken when driving vehicles and engaging in other potentially hazardous activities requiring increased attention and speed of psychomotor reactions. The bottle must be closed after each use.Do not touch the tip of the pipette to the eye.

Form release / dosage:

Eye drops 0.1% solution.

Packaging:

For 5 and 10 ml in plastic bottles with dispenser-dropper.

One bottle together with instructions for medical use is packed in a pack of cardboard.

Storage conditions:At a temperature of no higher than 25 ° C. Keep out of the reach of children.

Shelf life:

3 years. The opened vial should not be stored for more than 30 days.

Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:On prescription

Registration number:LS-000149

Date of registration:16.03.2010

The owner of the registration certificate:FIRN M, ZAO FIRN M, ZAO Russia

Manufacturer: & nbsp

FIRN M, ZAO Republic of Belarus

Information update date: & nbsp19.02.2016

Illustrated instructions

Instructions

Diclofenaclong® (DiclofenacLong®)