From the gastrointestinal tract (GIT):
- more often 1% - abdominal pain, flatulence (sensation of bloating), diarrhea,digestive disorders, nausea, constipation, dyspepsia, anorexia, impaired hepatic function, increased "liver" enzymes, peptic ulcer with possible complications (perforation, bleeding), gastro-intestinal bleeding;
- less than 1% - vomiting, jaundice, melena, blood in stool, esophageal lesion, aphthous stomatitis, dry mouth, mucosal, hepatitis (possibly fulminant), hepatic necrosis, cirrhosis, gepatorenalny syndrome, pancreatitis, holetsistopankreatit, colitis, hemorrhagic colitis , exacerbation of ulcerative colitis or Crohn's disease, fulminant hepatitis.
From the nervous system:
- more often 1% - headache, dizziness;
- less than 1% - insomnia, drowsiness, depression, irritability, aseptic meningitis (usually in patients with systemic lupus erythematosus and other connective tissue diseases.), cramps, weakness, disorientation, nightmares, feelings of fear, violation of sensitivity, including . paresthesia, memory disorders, tremors, convulsions, anxiety, cerebrovascular disorders, mental disorders.
From the sense organs:
- more often 1% - noise in the ears;
- less than 1% - blurred vision, diplopia, a taste disorder, reversible or irreversible hearing loss, scotoma.
From the skin:
- more often 1% - skin rash;
- less than 1% - urticaria, bullous eruptions, eczema, incl. multiform and Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), exfoliative dermatitis, toxic dermatitis, itching, hair loss, photosensitivity of purpura, incl. allergic.
From the genitourinary system:
- more often 1% - fluid retention;
less than 1% - nephrotic syndrome, proteinuria, oliguria, hematuria, interstitial nephritis, papillary necrosis, acute renal failure, azotemia.
From the organs of hematopoiesis and the immune system:
- Less than 1% - anemia (including hemolytic and aplasticaanemia), leukopenia, thrombocytopenia, eosinophilia, agranulocytosis, thrombocytopenic purpura, worsening of the course of infectious processes (development of necrotizing fasciitis, pneumonia).
From the respiratory system:
- less than 1% - cough, bronchospasm, laryngeal edema, pneumonitis, bronchial asthma (including, dyspnea).
From the cardiovascular system:
- less than 1% - increased blood pressure (BP), congestive heart failure, extrasystole, chest pain, palpitations, vasculitis, myocardial infarction.
Allergic reactions:
- less than 1% - anaphylactic / anaphylactoid reactions, including a marked decrease in blood pressure and shock (usually develops rapidly), swelling of the lips and tongue, allergic vasculitis.
Local reactions with intramuscular injection:
burning, infiltration, aseptic necrosis, necrosis of adipose tissue.