Diclofenac - instructions for use, dose, side effects, contraindications

Pharmacodynamics:Active component - diclofenac - non-steroidal anti-inflammatory drug, which has pronounced analgesic and anti-inflammatory properties. Indiscriminately inhibiting cyclooxygenase type 1 and 2, disrupts the metabolism of arachidonic acid and the synthesis of prostaglandins, which are the main link in the development of inflammation. Diclofenac It is used to eliminate the pain syndrome and reduce the swelling associated with the inflammatory process.With the recommended method of applying the drug, no more than 6% of diclofenac is absorbed.

Pharmacokinetics:

Indications:

- Diseases of the musculoskeletal system: rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, osteoarthritis of peripheral joints and spine: rheumatic soft tissue injuries.

- Muscular pain of rheumatic and non-rheumatic origin.

- Traumatic injuries of soft tissues.

Contraindications:

Hypersensitivity to diclofenac or other components of the drug, acetylsalicylic acid or other NSAIDs, aspirin asthma, pregnancy (III trimester), lactation period, children's age (up to 6 years), violation of the integrity of the skin.

Carefully:Hepatic porphyria (exacerbation), erosive and ulcerative lesions of the gastrointestinal tract, severe violations of liver and kidney function, chronic heart failure, bronchial asthma, advanced age, children under 12, pregnancy I and II trimester.

Pregnancy and lactation:The drug should not be used in the III trimester of pregnancy. Experience in the use of diktophenac in the lactation period is not available.Use in I and II trimesters is possible only after consultation with a doctor.

Dosing and Administration:Outwardly. Adults and children older than 6 years of the drug is applied to the skin 3-4 times a day and lightly rubbed. The required amount of the drug depends on the size of the painful area. A single dose of the drug -2-4 g (4-8 cm with a fully open neck of the tube). The duration of treatment without consulting a doctor should not exceed 10 days.

Side effects:

Local reactions: eczema, photosensitivity, contact dermatitis (itching, redness, swelling of the treated area of the skin, papules, vesicles, peeling).

Systemic reactions: generalized skin rash, allergic reactions (urticaria, anchoneurotic edema, bronchospastic reactions), photosensitization.

Overdose:Extremely low systemic absorption of active components of the drug with external application makes an overdose almost impossible.

Interaction:Diclofenac can enhance the effect of drugs that cause photosensitivity. Clinically significant interaction with other drugs has not been described.

Special instructions:Diclofenac Should be applied only to intact skin, avoiding contact with open wounds. After applying, do not apply an occlusive dressing. Do not allow the product to get into the eyes and mucous membranes.

Form release / dosage:Gel for external use 1%.

Packaging:30 grams per aluminum tube, lacquered from the inside, protected at the exit by an aluminum diaphragm, equipped with a plastic cap with a special device for piercing the diaphragm; 1 tube in a cardboard box together with instructions for use.

Storage conditions:

List B.

In a dry, dark place, out of the reach of children, at a temperature of 15 ° C to 25 ° C. Do not freeze.

Shelf life:

3 years.

Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:LS-000141

Date of registration:06.05.2010

The owner of the registration certificate:ELFA NPC, CJSC ELFA NPC, CJSC Russia

Manufacturer: & nbsp

INDUS PHARMA, PVT. Ltd. India

Information update date: & nbsp17.02.2016

Illustrated instructions

Instructions

Diclofenac (Diclofenac)