Undesirable reactions are mainly characterized by moderately expressed and passing skin manifestations at the place of patch application.
Very rare manifestations (< 1/10000):
Local reactions: pustular eruptions.
Systemic reactions: generalized skin rash; allergic reactions (hives, hypersensitivity: angioedema, asthma attacks, bronchospastic reactions), photosensitivity reactions.
Rare (≥1/10000, 1/1000):
Local reactions: bullous dermatitis.
Frequent manifestations (≥1/100, < 1/ 10):
Local reactions: erythema, dermatitis, incl. contact dermatitis (symptoms: erythema, pruritus, edema of the treated area of the skin, rash, papules, vesicles, peeling), eczema..