From the gastrointestinal tract: nausea, vomiting, diarrhea, epigastric pain, abdominal cramps, dyspepsia, flatulence, anorexia, constipation; In rare cases, the occurrence of erosive and ulcerative lesions, bleeding and perforation of the gastrointestinal tract.
From the nervous system: sometimes there is headache, dizziness, sleep disturbances (insomnia or drowsiness), excitement, in some cases, marked sensitivity disorders, disorientation, memory impairment, sight, hearing, taste sensations, tinnitus, cramps, irritability, tremor, mental disorders, depression, anxiety, aseptic meningitis.
Allergic manifestations: sometimes a skin rash occurs, seldom - hives, individual cases of eczema, polymorphic erythema, erythroderma,rarely had attacks of bronchial asthma, systemic anaphylactic reactions, in some cases, vasculitis, pneumonitis.
From the side of the kidneys: rarely edema, in acute cases, acute renal failure, interstitial nephritis, nephrotic syndrome, hematuria, proteinuria.
From the side of the liver: transient increase in transaminase activity in the blood, rarely - hepatitis, in some cases fulminant hepatitis.
On the part of the hematopoiesis system: individual cases of development of thrombocytopenia, agranulocytosis, hemolytic anemia, aplastic anemia are described.
From the side of the cardiovascular system: single cases of tachycardia, arterial hypertension, congestive heart failure were noted.