Diklogen - instructions for use, dosage, side effects, contraindications

Chlorocerol, liquid paraffin, carbomer 940, disodium edetate, propylene glycol, isopropanol, benzyl alcohol, sodium sulfite, polysorbate 80, lavender oil, trolamine, purified water.

Description:Almost white translucent gel with a specific odor.

Pharmacotherapeutic group:Non-steroidal anti-inflammatory drug (NSAID).

ATX: & nbsp

S.01.B.C.03 Diclofenac

M.01.A.B.05 Diclofenac

Pharmacodynamics:

The active component of the drug diclofenac - Non-steroidal anti-inflammatory drug (NSAID), which has pronounced analgesic (analgesic) and anti-inflammatory properties. Indiscriminately inhibiting cyclooxygenase type 1 and 2, disrupts the metabolism of arachidonic acid and the synthesis of prostaglandins, which are the main link in the development of inflammation.

Diklogen® is used to eliminate the pain syndrome and reduce the swelling associated with the inflammatory process.When topical application causes weakening or disappearance of pain in joints at rest and during movement. Reduces the morning stiffness and swelling of the joints, contributes to an increase in the volume of movements.

Pharmacokinetics:At application system absorption is no more than 6%. The connection with proteins is 99.7%. It is excreted by the kidneys.

Indications:

- Post-traumatic inflammation of soft tissues and joints, for example due to stretching, overstrain and bruises.

- Rheumatic diseases of soft tissues (tendovaginitis, bursitis, lesion of periarticular tissues);

- Pain and swelling associated with muscle disease and joints (rheumatoid arthritis, osteoarthritis, radiculitis, lumbago, sciatica, muscular pain of rheumatic and rheumatic proiskhodzheniya).

Contraindications:Hypersensitivity to diclofenac or other components of the drug, acetylsalicylic acid or other NSAIDs, anamnestic data on a bronchial asthma attack, rhinitis, urticaria after taking acetylsalicylic acid or other NSAIDs, pregnancy (III trimester), lactation period, children's age (up to 6 years), violation the integrity of the skin.

Carefully:hepatic porphyria (exacerbation), erosive-ulcerative lesions of the gastrointestinal tract, severe violations of the liver and kidney function, impaired blood clotting (including hemophilia, prolonged bleeding time, a tendency to bleeding), chronic heart failure, bronchial asthma, elderly age, pregnancy I and II trimester.

Pregnancy and lactation:The drug should not be used in the III trimester of pregnancy. Experience with the drug during lactation is not available. Use in I and II trimesters is possible only after consultation with a doctor.

Dosing and Administration:Outwardly. Adults and children over 12 years of age, the drug is applied to the skin 2 times a day and lightly rubbed. The required amount of the drug depends on the size of the painful area. A single dose of the drug - up to 2 g (about 4 cm with a fully open neck of the tube). Children from 6 to 12 years of age should not be used more than 2 times a day, a single dose of the drug to 1 g (about 2 cm with a fully open neck of the tube).

After applying the product, the hands should be washed.

The duration of treatment depends on the indications and the therapeutic effect. After 2 weeks of use, consult a physician.

Side effects:

Local reactions: eczema, photosensitivity, contact dermatitis (itching, redness, swelling of the treated area of the skin, papules, vesicles, peeling).

Systemic reactions: generalized skin rash, allergic reactions (hives, angioedema, bronchospastic reactions), photosensitization.

Overdose:Extremely low systemic absorption of the active components of the drug makes an overdose virtually impossible. In case of accidental ingestion of large amounts of gel (more than 20 g), systemic undesirable reactions characteristic of NSAIDs are possible. It is necessary to wash the stomach, taking activated charcoal.

Interaction:The drug may enhance the effect of drugs that cause photosensitivity. Clinically significant interaction with other drugs has not been described.

Special instructions:

The gel should only be applied to intact skin, avoiding contact with open wounds. After applying, do not apply an occlusive dressing. Do not allow the product to get into the eyes and mucous membranes.

With prolonged use of large amounts of the drug, it is impossible to exclude the occurrence of systemic side effects, characteristic for NSAIDs.

Form release / dosage:

Gel for external use 1%.

Packaging:30 g or 50 g of gel in an aluminum or aluminum laminated tube. 1 tube with instructions for use in a cardboard pack.

Storage conditions:Store in a dry, dark place at a temperature of no higher than 25 ° C. Do not freeze.

Keep out of the reach of children.

Shelf life:3 years. Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:П N013706 / 01

Date of registration:07.10.2008

The owner of the registration certificate:Agio Pharmaceuticals Ltd.Agio Pharmaceuticals Ltd. India

Manufacturer: & nbsp

AGIO PHARMACEUTICALS, Ltd. India

Representation: & nbspAgio Pharmaceuticals Ltd.Agio Pharmaceuticals Ltd.

Information update date: & nbsp27.02.2016

Illustrated instructions

Instructions

Diklogen® (Diclogen®)