Active substanceDiclofenacDiclofenac
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  • Dosage form: & nbspointment for external use
    Composition:
    Active substance: sodium diclofenac 2.0 g;
    Excipients - Arepol, carbomer, benzyl benzoate, nipagin, propyl ester of p-hydroxybenzoic acid (nipazole), Tween-80, purified water.
    Description:Homogeneous ointment white with a grayish cream color shade.
    Pharmacotherapeutic group:Non-steroidal anti-inflammatory drug
    ATX: & nbsp

    S.01.B.C.03   Diclofenac

    M.01.A.B.05   Diclofenac

    Pharmacodynamics:Has anti-inflammatory and analgesic effect. Inhibiting cycloxygenase 1 and 2, disrupts the metabolism of arachidonic acid, reduces the amount of prostaglandins in the inflammation focus. Water-alcohol base - additionally has a local anesthetic effect.
    Indications:
    Inflammatory diseases of the musculoskeletal system (rheumatoid arthritis, psoriatic, juvenile chronic arthritis, ankylosing spondylitis, gouty arthritis); traumatically caused inflammation of the tendons, ligaments, muscles and joints (as a result of stretching, with the load and bruises).
    Pain syndrome (lumbago, sciatica, myalgia neuralgia, tendovaginitis, bursitis, rheumatic soft tissue disorders, degenerative diseases of the musculoskeletal system: deforming osteoarthritis, osteochondrosis).
    Contraindications:Hypersensitivity (including other NSAIDs), erosive and ulcerative lesions of the gastrointestinal tract (in the phase of exacerbation), "aspirin" asthma, hematopoiesis, pregnancy (III trimester), younger children (up to 6 years), lactation period, violation of the integrity of the skin.
    Carefully:Hepatic porphyria (exacerbation), severe impairment of liver and kidney function, heart failure, elderly age.
    Dosing and Administration:Outwardly. Ointment - 2-4 g is applied in a thin layer, lightly rubbing into the skin, over the inflammation focus 2-3 times a day. The maximum daily dose is 8 g. The course of treatment is 7-14 days. Ointment - 2-4 g (the size of a walnut or cherry), depending on the area of ​​the painful focus, apply 3-4 times a day on the affected areas and gently rub (can be used to enhance the effect together with other medicinal forms of diclofenac); After application, wash hands.
    Side effects:

    From the skin: allergic reactions (skin itching, erythematous and urticaria skin rash, burning, angioedema, systemic anaphylactic reactions (including shock), eczema, photosensitivity.

    With long-term use and / or application on extensive surfaces - systemic side effects due to resorptive action.

    From the digestive system: NSAIDs-gastropathy (gastralgia, vomiting, diarrhea, abdominal pain, flatulence), erosive and ulcerative lesions of the digestive tract, gastrointestinal bleeding, increased activity of "liver" transaminases, toxic hepatitis (with jaundice or without jaundice).

    From the nervous system: headache, dizziness, fatigue, insomnia, anxiety, "nightmarish" dreams, a violation of taste sensations.

    From the sense organs: reduction of visual acuity, diplopia, scotoma, hearing loss, tinnitus.

    From the urinary system: nephrotic syndrome.

    From the hematopoiesis: thrombocytopenia, leukopenia, anemia.

    From the respiratory system: bronchospasm.

    From the CAS side: heart palpitations, chest pain, arrhythmias; increase in blood pressure.

    Overdose:

    With an external application of the ointment, an overdose is unlikely. However, when applying ointment to large areas of the skin and with prolonged use, the possibility of systemic side effects of diclofenac can not be completely ruled out.

    Interaction:To date, no interaction has been reported with Orthofer ® with other drugs.
    Special instructions:
    Apply only to undamaged skin. After applying, do not apply an occlusive bandage.
    When applied to large areas of the skin for a long time, the risk of systemic side effects increases.
    Avoid contact with eyes, mucous membranes or open wounds.
    Use only as an external product.
    Form release / dosage:Ointment for external use 2%.
    Packaging:For 20, 30 g of the drug in tubes.
    Storage conditions:In a cool and dry place inaccessible to children.
    Shelf life:2 years and 6 months. Do not use the drug after the expiration date.
    Terms of leave from pharmacies:Without recipe
    Registration number:P N002288 / 01-2003
    Date of registration:15.08.2008
    Expiration Date:Unlimited
    The owner of the registration certificate:BRYNTSALOV-A, CJSC BRYNTSALOV-A, CJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp12.06.2017
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