From the gastrointestinal tract:
more often 1%- abdominal pain or spasm, sensation of bloating, diarrhea, nausea, constipation, flatulence, increased activity of "liver" tranaminaz; peptic ulcer with possible complications (bleeding, perforation), gastrointestinal bleeding without ulcers;
less often 1% - vomiting, jaundice, melena, blood in the doghouse, esophageal lesion, aphthous stomatitis, dryness of mucous membranes (including the mouth), hepatitis (possibly fulminant course), hepatic necrosis, cirrhosis, hepatorenal syndrome, appetite change, pancreatitis (in including those with concomitant hepatitis), holetsistopankreatit colitis.
From the nervous system: more often 1% - headache, dizziness;
less than 1% - sleep disturbance, drowsiness, depression, irritability, aseptic meningitis (more often in patients with systemic lupus erythematosus and other systemic connective tissue diseases), convulsions, general weakness, disorientation, nightmares, fear.
From the sense organs:
more often 1% - noise in the ears;
On the part of the skin :, more often 1% - skin itch, skin rash;
less often 1% - alopecia, urticaria, eczema, toxic dermatitis, multiforme exudative erythema (including Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell syndrome), increased photosensitivity, small-point hemorrhages.
From the genitourinary system:
more often 1% - fluid retention;
less than 1% - nephrotic syndrome, proteinuria, oliguria, hematuria, interstitial nephritis, papillary necrosis, acute renal failure, azotemia.
From the organs of hematopoiesis and the immune system: less than 1% - anemia (including hemolytic and aplastic anemia), leukopenia, thrombocytopenia, eosinophilia, agranulocytosis, thrombocytopenic purpura, worsening of the course of infectious processes (including the development of necrotizing fasciitis).
From the respiratory system:
less than 1% - cough, bronchospasm, laryngeal edema, pneumonitis.
From the cardiovascular system:
less than 1% - increased blood pressure; congestive heart failure, extrasystole, chest pain.
Allergic reactions:
less often 1% - anaphylactoid reactions, anaphylactic shock (usually develops rapidly), swelling of the lips and tongue, allergic vasculitis.