Diclofenac - instructions for use, dose, side effects, contraindications

Excipients: rectified ethyl alcohol, propylene glycol, carbopol (carbomer), nipagin (methyl parahydroxybenzoate), triethanolamine, lavender oil, purified water.

Description:Homogeneous, translucent, white or white with a yellowish or creamy shade gel with a specific odor.

Pharmacotherapeutic group:Non-steroidal anti-inflammatory drug (NSAID).

ATX: & nbsp

S.01.B.C.03 Diclofenac

M.01.A.B.05 Diclofenac

Pharmacodynamics:Active component diclofenac - non-steroidal anti-inflammatory drug, which has pronounced analgesic and anti-inflammatory properties. Indiscriminately inhibiting cyclooxygenase type 1 and 2, disrupts the metabolism of arachidonic acid and the synthesis of prostaglandins, which are the main link in the development of inflammation. Diclofenac Used to eliminate pain syndrome and reduce swelling,related to the inflammatory process. With the recommended method of applying the drug, no more than 6% of diclofenac is absorbed.

Pharmacokinetics:

Indications:

- Post-traumatic inflammation of soft tissues and joints, for example due to stretching, overstrain and bruises.

- Rheumatic diseases of soft tissues (tendovaginitis, bursitis, percuticular tissue lesions);

- Pain syndrome and puffiness associated with diseases of the muscles and joints (rheumatoid arthritis, osteoarthritis, radiculitis, lumbago, sciatica).

Contraindications:Hypersensitivity to diclofenac or other components of the drug, as well as to salicylates or other non-steroidal anti-inflammatory drugs, an indication in an anamnesis for seizures of bronchial asthma after the administration of NSAIDs and salicylates; pregnancy (III trimester), lactation period, children's age (up to 6 years), violation of the integrity of the skin.

Carefully:

hepatic porphyria (exacerbation), erosive and ulcerative lesions of the gastrointestinal tract, severe liver and kidney disease, chronic heart failure, bronchial asthma, advanced age, pregnancy I and II trimester.

Pregnancy and lactation:The drug should not be used in the III trimester of pregnancy. Experience in using the drug during lactation is not available. Use in I and II trimesters is possible only after consultation with a doctor.

Dosing and Administration:Outwardly. Adults and children over 12 years of age, the drug is applied to the skin 3-4 times a day and lightly rubbed. The required amount of the drug depends on the size of the painful area. A single dose of the drug is 2-4 g (which is comparable in volume to the size of a cherry or walnut, respectively). Children from 6 to 12 years should use no more than 2 g of the drug up to 2 times a day. After applying the product, the hands should be washed. The duration of treatment depends on the indications and the effect observed. After 2 weeks of use, consult a physician.

Side effects:Local reactions: eczema, photosensitivity, contact dermatitis (itching, redness, swelling of the treated area of the skin, papules, vesicles, peeling). Systemic reactions: generalized skin rash, allergic reactions (hives, angioedema, bronchospastic reactions), photosensitization.

Overdose:Extremely low systemic absorption of active components of the drug with external application makes an overdose almost impossible.

Interaction:The drug may enhance the effect of drugs that cause photosensitivity. Clinically significant interaction with other drugs has not been described.

Special instructions:The gel should only be applied to intact skin, avoiding contact with open wounds. After applying, do not apply an occlusive dressing. Do not allow the product to get into the eyes and mucous membranes.

Form release / dosage:

Gel for external use 1%.

Packaging:

By 20 g, 30 g and 50 g in aluminum tubes or in tubes laminated. Each tube together with the instruction for use is placed in a pack of cardboard.

Storage conditions:At a temperature of 15 to 25 ° C. Freezing is not allowed. Keep out of the reach of children.

Shelf life:

3 years. Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:LSR-000076

Date of registration:28.05.2007 / 22.12.2014

Expiration Date:Unlimited

The owner of the registration certificate:SYNTHESIS, OJSC SYNTHESIS, OJSC Russia

Manufacturer: & nbsp

SYNTHESIS, OJSC Russia

Information update date: & nbsp19.10.2016

Illustrated instructions

Instructions

Diclofenac (Diclofenac)